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Volume 24, Number 2—February 2018
Research

Multiplex PCR−Based Next-Generation Sequencing and Global Diversity of Seoul Virus in Humans and Rats

Won-Keun Kim1, Jin Sun No1, Seung-Ho Lee, Dong Hyun Song, Daesang Lee, Jeong-Ah Kim, Se Hun Gu, Sunhye Park, Seong Tae Jeong, Heung-Chul Kim, Terry A. Klein, Michael R. Wiley, Gustavo Palacios, and Jin-Won SongComments to Author 
Author affiliations: Korea University, Seoul, South Korea (W.-K. Kim, J.S. No, S.-H. Lee, J.-A. Kim, J.-W. Song); Agency for Defense Development, Daejeon, South Korea (D.H. Song, D. Lee, S.H. Gu, S. Park, S.T. Jeong); 65th Medical Brigade/Medical Department Activity−Korea, Seoul (H.-C. Kim, T.A. Klein); US Army Medical Research Institute of Infectious Disease, Fort Detrick, Maryland, USA (M.R. Wiley, G. Palacios)

Main Article

Table 2

Serologic and molecular prevalence of SEOV in Rattus norvegicus rats, by metropolitan area/province, sex, weight, and season, South Korea, 2000–2016*

Characteristic No. rats Prevalence of IgG against SEOV, no. positive/no. tested (%) SEOV RNA, no. positive/no. tested (%)
Region, n = 1,269
Seoul 1,226 76/1,226 (6.2) 13/76 (17.1%)
Gyeonggi Province 40 1/40 (2.5) 0/1
Gangwon Province 1 0/1 (0) ND
Jeollanam Province 2 0/2 (0) ND
Sex, n = 1,269
M 576 43/576 (7.5) 9/43 (21.0)
F 684 34/684 (5.0) 4/34 (11.8)
Unknown 9 0/9 (0) 0/9 (0)
Weight, g, n = 1,269
<50 342 21/342 (6.1) 2/21 (9.5)
51–100 374 22/374 (5.9) 3/22 (13.6)
101–200 521 30/521 (5.8) 7/30 (23.3)
201–300 29 4/29 (13.8) 1/4 (25.0)
Unknown 3 0/3 (0) ND
Season, n = 1,269
Spring, Mar–May 190 11/190 (5.8) 0/11 (0)
Summer, Jun–Aug 433 19/433 (4.4) 2/19 (10.5)
Fall, Sep–Nov 420 27/420 (6.4) 6/27 (22.2)
Winter, Dec–Feb 190 19/190 (10.0) 5/19 (26.3)
Unknown 36 1/36 (2.8) 0/1 (0)

*ND, not determined; SEOV, Seoul virus.

Main Article

1These authors contributed equally to this article.

Page created: January 17, 2018
Page updated: January 17, 2018
Page reviewed: January 17, 2018
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