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Volume 24, Number 3—March 2018
Research

Use of Influenza Risk Assessment Tool for Prepandemic Preparedness

Stephen A. BurkeComments to Author  and Susan C. Trock
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (S.C. Trock, S.A. Burke); Battelle, Atlanta (S.A. Burke)

Main Article

Table 1

Emergence question IRAT score calculation for 2 similar influenza A(H7N9) viruses, A/Shanghai/2/2013 and A/Anhui/1/2013, with data missing on the risk element “transmission in laboratory animals” during scoring of 2013 outbreak in China*

R = 1†
R = 7‡
R = 10§
R
W × R
R
W × R
R
W × R
Human infections 0.2929 5.00 1.46 1.46 1.46
Transmission in lab animals 0.1929 1.00 0.19 7.00 1.35 10.00 1.93
Receptor binding 0.1429 6.70 0.96 0.96 0.96
Population immunity 0.1096 9.00 0.99 0.99 0.99
Infections in animals 0.0846 6.00 0.51 0.51 0.51
Genomic variation 0.0646 8.60 0.56 0.56 0.56
Antigenic relatedness 0.0479 6.00 0.29 0.29 0.29
Global distribution in animals 0.0336 1.00 0.03 0.03 0.03
Disease severity and pathogenesis 0.0211 9.00 0.19 0.19 0.19
Antiviral drug and treatment options
0.0100
5.40
0.05


0.05


0.05
Total 1.0001 5.24 6.40 6.98

*IRAT, Influenza Risk Assessment Tool; R, average risk point score; W, weight.
†Substituting the lowest possible risk score (1) to calculate summary IRAT score.
‡Substituting a moderate risk score (7) to calculate summary IRAT score.
§Substituting the highest possible risk score (10) to calculate summary IRAT score.

Main Article

Page created: February 15, 2018
Page updated: February 15, 2018
Page reviewed: February 15, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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