Volume 24, Number 3—March 2018
Research
Use of Influenza Risk Assessment Tool for Prepandemic Preparedness
Table 1
Emergence question IRAT score calculation for 2 similar influenza A(H7N9) viruses, A/Shanghai/2/2013 and A/Anhui/1/2013, with data missing on the risk element “transmission in laboratory animals” during scoring of 2013 outbreak in China*
R = 1† | R = 7‡ | R = 10§ | |||||||
---|---|---|---|---|---|---|---|---|---|
R |
W × R |
R |
W × R |
R |
W × R |
||||
Human infections | 0.2929 | 5.00 | 1.46 | 1.46 | 1.46 | ||||
Transmission in lab animals | 0.1929 | 1.00 | 0.19 | 7.00 | 1.35 | 10.00 | 1.93 | ||
Receptor binding | 0.1429 | 6.70 | 0.96 | 0.96 | 0.96 | ||||
Population immunity | 0.1096 | 9.00 | 0.99 | 0.99 | 0.99 | ||||
Infections in animals | 0.0846 | 6.00 | 0.51 | 0.51 | 0.51 | ||||
Genomic variation | 0.0646 | 8.60 | 0.56 | 0.56 | 0.56 | ||||
Antigenic relatedness | 0.0479 | 6.00 | 0.29 | 0.29 | 0.29 | ||||
Global distribution in animals | 0.0336 | 1.00 | 0.03 | 0.03 | 0.03 | ||||
Disease severity and pathogenesis | 0.0211 | 9.00 | 0.19 | 0.19 | 0.19 | ||||
Antiviral drug and treatment options |
0.0100 |
5.40 |
0.05 |
0.05 |
0.05 |
||||
Total | 1.0001 | 5.24 | 6.40 | 6.98 |
*IRAT, Influenza Risk Assessment Tool; R, average risk point score; W, weight.
†Substituting the lowest possible risk score (1) to calculate summary IRAT score.
‡Substituting a moderate risk score (7) to calculate summary IRAT score.
§Substituting the highest possible risk score (10) to calculate summary IRAT score.