Volume 24, Number 3—March 2018
Research
Use of Influenza Risk Assessment Tool for Prepandemic Preparedness
Stephen A. Burke
and Susan C. Trock
and Susan C. Trock
Table 2
Impact question IRAT score calculation for 2 similar influenza A(H7N9) viruses, A/Shanghai/2/2013 and A/Anhui/1/2013, with data missing on the risk element “transmission in laboratory animals” during scoring of 2013 outbreak in China*
| R = 1† | R = 7‡ | R = 10§ | |||||||
|---|---|---|---|---|---|---|---|---|---|
| R |
W × R |
R |
W × R |
R |
W × R |
||||
| Disease severity and pathogenesis | 0.2929 | 9.00 | 2.64 | 2.64 | 2.64 | ||||
| Population immunity | 0.1929 | 9.00 | 1.74 | 1.74 | 1.74 | ||||
| Human infections | 0.1429 | 5.00 | 0.71 | 0.71 | 0.71 | ||||
| Antiviral drug and treatment options | 0.1096 | 5.40 | 0.59 | 0.59 | 0.59 | ||||
| Antigenic relatedness | 0.0846 | 6.00 | 0.51 | 0.51 | 0.51 | ||||
| Receptor binding | 0.0646 | 6.70 | 0.43 | 0.43 | 0.43 | ||||
| Genomic variation | 0.0479 | 8.60 | 0.41 | 0.41 | 0.41 | ||||
| Transmission in lab animals | 0.0336 | 1.00 | 0.03 | 7.00 | 0.24 | 10.00 | 0.34 | ||
| Global distribution in animals | 0.0211 | 1.00 | 0.02 | 0.02 | 0.02 | ||||
| Infection in animals |
0.0100 |
6.00 |
0.06 |
0.06 |
0.06 |
||||
| Total | 1.0001 | 7.14 | 7.35 | 7.45 | |||||
*IRAT, Influenza Risk Assessment Tool; R, average risk point score; W, weight.
†Substituting the lowest possible risk score (1) to calculate summary IRAT score.
‡Substituting a moderate risk score (7) to calculate summary IRAT score.
§Substituting the highest possible risk score (10) to calculate summary IRAT score.
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