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Volume 24, Number 3—March 2018
Research

Use of Influenza Risk Assessment Tool for Prepandemic Preparedness

Stephen A. BurkeComments to Author  and Susan C. Trock
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (S.C. Trock, S.A. Burke); Battelle, Atlanta (S.A. Burke)

Main Article

Table 4

Product of average risk point scores multiplied by weight for each of the 10 influenza A(H5N1) clades for the IRAT when the antigenic relatedness score is based on the virus’ relatedness to a US stockpiled antigen*

Element
Clade
1.1.1
1.1.2
2.1.3.2a
2.2.1
2.2.1.1
2.3.2.1a
2.3.2.1b
2.3.2.1c
2.3.4.2
7.2
Human infections 1.96 3.06 2.28 2.28 0.91 1.96 1.05 1.83 1.83 0.59
Antigenic relatedness to stockpiled antigen 0.77 1.21 1.28 0.69 2.05 1.98 1.98 1.98 1.62 2.05
Global distribution in animals 0.63 0.78 0.78 0.47 0.47 0.94 0.89 1.21 0.74 0.67
Infection in animals 0.45 0.63 0.63 0.66 0.27 0.57 0.48 0.72 0.51 0.42
Genomic variation
0.12
0.25
0.13
0.13
0.18
0.16
0.12
0.25
0.11
0.19
Total 3.93 5.94 5.11 4.23 3.78 5.61 4.52 5.99 4.80 3.93

*Weight for human infections = 0.4567; weight for antigenic relatedness to candidate vaccine virus = 0.2567; weight for global distribution in animals = 0.1567; weight for infections in animals = 0.09; weight for genomic variation = 0.04. IRAT, Influenza Risk Assessment Tool.

Main Article

Page created: February 15, 2018
Page updated: February 15, 2018
Page reviewed: February 15, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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