Volume 24, Number 3—March 2018
Research
Use of Influenza Risk Assessment Tool for Prepandemic Preparedness
Stephen A. Burke
and Susan C. Trock
and Susan C. Trock
Table 3
Product of average risk point scores multiplied by weight for each of the 10 influenza A(H5N1) clades for the IRAT when the antigenic relatedness score is based on the virus’ relatedness to a CVV*
| Element |
Clade |
|||||||||
| 1.1.1 |
1.1.2 |
2.1.3.2a |
2.2.1 |
2.2.1.1 |
2.3.2.1a |
2.3.2.1b |
2.3.2.1c |
2.3.4.2 |
7.2 |
|
| Human infections | 1.96 | 3.06 | 2.28 | 2.28 | 0.91 | 1.96 | 1.05 | 1.83 | 1.83 | 0.59 |
| Antigenic relatedness to CVV | 0.59 | 0.69 | 0.59 | 0.59 | 1.54 | 0.59 | 0.59 | 0.59 | 0.69 | 2.05 |
| Global distribution in animals | 0.63 | 0.78 | 0.78 | 0.47 | 0.47 | 0.94 | 0.89 | 1.21 | 0.74 | 0.67 |
| Infection in animals | 0.45 | 0.63 | 0.63 | 0.66 | 0.27 | 0.57 | 0.48 | 0.72 | 0.51 | 0.42 |
| Genomic variation |
0.12 |
0.25 |
0.13 |
0.13 |
0.18 |
0.16 |
0.12 |
0.25 |
0.11 |
0.19 |
| Total | 3.75 | 5.42 | 4.42 | 4.13 | 3.27 | 4.22 | 3.13 | 4.60 | 3.87 | 3.93 |
*Weight for human infections = 0.4567; weight for antigenic relatedness to CVV = 0.2567; weight for global distribution in animals = 0.1567; weight for infections in animals = 0.09; weight for genomic variation = 0.04. CVV, candidate vaccine virus; IRAT, Influenza Risk Assessment Tool.
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