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Volume 26, Number 2—February 2020
Research

Novel Subclone of Carbapenem-Resistant Klebsiella pneumoniae Sequence Type 11 with Enhanced Virulence and Transmissibility, China

Kai Zhou1, Tingting Xiao1, Sophia David1, Qin Wang, Yanzi Zhou, Lihua Guo, David Aanensen, Kathryn E. Holt, Nicholas R. Thomson, Hajo Grundmann2, Ping Shen2, and Yonghong Xiao2Comments to Author 
Author affiliations: First Affiliated Hospital of Southern University of Science and Technology (Shenzhen People’s Hospital); Shenzhen, China (K. Zhou); The Second Clinical Medical College of Jinan University, Shenzhen (K. Zhou); Zhejiang University, Hangzhou, China (T. Xiao, Q. Wang, Y. Zhou, L. Guo, P. Shen, Y. Xiao); Centre for Genomic Pathogen Surveillance, Cambridge, UK (S. David, D. Aanensen); University of Melbourne, Melbourne, Victoria, Australia (K.E. Holt); London School of Hygiene and Tropical Medicine, London, UK (K.E. Holt, N.R. Thomson); Wellcome Trust Sanger Centre, Cambridge (N.R. Thomson); University of Freiburg, Freiburg, Germany (H. Grundmann)

Main Article

Table 2

Cox regression of multivariable analysis of risk factors for 30-day mortality in 191 BSI patients infected with carbapenem-resistant Klebsiella pneumoniae, China, 2013–2017*

Variable p value† OR (95% CI)
Platelets at time of BSI
 0.001
 0.996 
(0.994–0.998)
APACHE II score at time of BSI
 0.012
 1.041 
(1.009–1.074
Tigecycline as empirical therapy 0.003 1.920 
(1.257–2.935)

*APACHE, Acute Physiology and Chronic Health Evaluation; BSI, bloodstream infection; OR, odds ratio.
†Calculated by using Cox regression.

Main Article

1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.

Page created: January 17, 2020
Page updated: January 17, 2020
Page reviewed: January 17, 2020
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