Stable and Local Reservoirs of Mycobacterium ulcerans Inferred from the Nonrandom Distribution of Bacterial Genotypes, Benin
Clément Coudereau, Alban Besnard, Marie Robbe-Saule, Céline Bris, Marie Kempf, Roch Christian Johnson, Télésphore Yao Brou, Ronald Gnimavo, Sara Eyangoh, Fida Khater, and Estelle Marion
Author affiliations: Université d’Angers, Angers, France (C. Coudereau, A. Besnard, M. Robbe-Saule, M. Kempf, F. Khater, E. Marion); INSERM, Angers (C. Coudereau, A. Besnard, M. Robbe-Saule, M. Kempf, F. Khater, E. Marion); Centre Hospitalo-Universitaire d’Angers, Angers (C. Bris, M. Kempf); Université d'Abomey Calavi, Abomey Calavi, Benin (R.C. Johnson); Fondation Raoul Follereau, Paris, France (R.C. Johnson); Maison de la Télédétection, Montpellier, France (T.Y. Brou); Centre de Diagnostic et Traitement de la Lèpre et de l’Ulcère de Buruli, Pobè, Bénin (R. Gnimavo); International Pasteur Institute Network, Yaoundé, Cameroon (S. Eyangoh)
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Figure 6
Figure 6. Spatial cluster detection results of Mycobacterium ulcerans genotype 8 for Buruli ulcer patients in Benin and Nigeria. Genotype 8 population was identified in 2 clusters along the Ouémé River. A) Phylogenetic tree of genotype 8 reveals the presence of potentially emerging genotypes. B) Location of the clusters. The analysis shows 2 significant clusters where specific subgenotypes are overrepresented compared to outside of these areas. C) Composition of these 2 clusters compared with the composition that would be expected from a random distribution.
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