Volume 28, Number 6—June 2022
Research
Risk Prediction Score for Pediatric Patients with Suspected Ebola Virus Disease
Table 1
Demographic and clinical characteristics of patients, by EVD status at triage, in West Africa, September 2014 – September 2015*
Characteristics | Total, no (%), n = 521 | EVD positive, no. (%), n = 120 (23%) | EVD negative, no. (%), n = 401 (77%) | OR (95% CI) | p value |
---|---|---|---|---|---|
Sex | |||||
M | 261 (50) | 53 (44) | 208 (52) | 0.73 (0.49–1.10) | 0.14 |
F |
260 (50) |
67 (56) |
193 (48) |
Referent |
|
Sign/symptom | |||||
Fever | 431 (83) | 95 (79) | 336 (84) | 0.74 (0.44–1.25) | 0.24 |
Headache | 268 (51) | 54 (45) | 214 (53) | 0.71 (0.47–1.08) | 0.11 |
Breathlessness | 84 (16) | 16 (13) | 68 (17) | 0.75 (0.41–1.33) | 0.35 |
Bone/muscle pain | 201 (39) | 43 (36) | 158 (39) | 0.86 (0.56–1.31) | 0.48 |
Asthenia | 333 (64) | 77 (64) | 256 (64) | 1.01 (0.67–1.56) | 0.95 |
Abdominal pain | 219 (42) | 29 (24) | 190 (47) | 0.35 (0.22–0.56) | <0.001 |
Hiccups | 39 (7.5) | 5 (4.2) | 34 (8.5) | 0.47 (0.16–1.13) | 0.12 |
Any bleeding | 77 (15) | 36 (30) | 41 (10) | 3.76 (2.26–6.25) | <0.001 |
GI symptoms |
355 (68) |
73 (61) |
282 (70) |
0.66 (0.43–1.01) |
0.05 |
Ebola contact | <0.001 | ||||
Yes | 218 (42) | 104 (87) | 114 (28) | 31.3 (15.1–76.1) | |
No known | 56 (11) | 9 (7.5) | 47 (12) | 6.57 (2.33–19.2) | |
No |
247 (47) |
7 (5.8) |
240 (60) |
Referent |
|
Malaria | 0.009 | ||||
Yes | 163 (31) | 27 (23) | 136 (34) | 0.42 (0.24–0.73) | |
Missing† | 233 (45) | 53 (44) | 180 (45) | 0.63 (0.39–1.02) | |
No | 125 (24) | 40 (33) | 85 (21) | Referent |
*Patient median age (interquartile range) = 7 (3–13) y; OR (95% CI) = 1.00 (0.97–1.04); p = 0.80. Boldface indicates statistical significance. EVD, Ebola virus disease; GI, gastrointestinal; OR, odds ratio. †Missing refers to patients who did not have a rapid diagnostic test completed or results not available.
1These authors contributed equally to this article.
2These authors contributed equally to this article.
3Current affiliation: Pediatric Infectious Diseases & Immunology, Connecticut Children’s Medical Center, Hartford, Connecticut, USA.