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Volume 29, Number 1—January 2023
Research

Seroepidemiology and Carriage of Diphtheria in Epidemic-Prone Area and Implications for Vaccination Policy, Vietnam

Noriko KitamuraComments to Author , Thanh T. Hoan, Hung M. Do, The A. Dao, Lien T. Le, Thao T.T. Le, Thuy T.T. Doan, Thuong N. Chau, Hoi T. Dinh, Masaaki Iwaki, Mitsutoshi Senoh, Androulla Efstraciou, Nen M. Ho, Duc M. Pham, Duc-Anh Dang, Michiko Toizumi, Paul Fine, Hung T. Do, and Lay-Myint Yoshida
Author affiliations: London School of Hygiene and Tropical Medicine, London, UK (N. Kitamura, P. Fine); Nagasaki University, Nagasaki, Japan (N. Kitamura, M. Toizumi, L.-M. Yoshida); Pasteur Institute in Nha Trang, Nha Trang, Vietnam (T.T. Hoan, H.M. Do, T.A. Dao, L.T. Le, T.T.T. Le, T.T.T. Doan, H.T. Do); Quang Ngai Provincial Health Services, Quang Ngai, Vietnam (T.N. Chau, H.T. Dinh, N.M. Ho, D.M. Pham); National Institute of Infectious Diseases, Tokyo, Japan (M. Iwaki, M. Senoh); National Institute of Hygiene and Epidemiology, Hanoi, Vietnam (D.-A. Dang); UK Health Security Agency, London (A. Efstraciou)

Main Article

Table 5

Associations between Corynebacterium diphtheriae carriage and diphtheria toxoid IgG levels adjusted for age assessed by logistic regression and between IgG levels and mid-upper arm circumference adjusted for age by linear regression, Vietnam*

Association between carriage status and IgG Crude odds ratio 95% CI) p value Adjusted odds ratio (95% CI) p value
log-transformed IgG level 1.49 (1.15‒1.93) <0.01 1.49 (1.17‒1.90) <0.01
Age, y
 0.94 (0.90‒0.97)
 <0.01
 0.94 (0.90‒0.97)
 <0.01
Association between IgG and MUAC
 Crude coefficient
 p value
 Adjusted coefficient
 p value
MUAC, cm 0.01 (‒0.01 to 0.02) 0.43 0.02 (0.00‒0.03) 0.014
Age, y
 ‒0.21 (‒0.34 to ‒0.08)
 <0.01
 ‒0.31 (‒0.45 to ‒0.16)
 <0.01
*MUAC, mid-upper arm circumference.

Main Article

Page created: November 01, 2022
Page updated: December 21, 2022
Page reviewed: December 21, 2022
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