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Volume 29, Number 2—February 2023
Research

Circovirus Hepatitis Infection in Heart-Lung Transplant Patient, France

Philippe Pérot1, Jacques Fourgeaud1, Claire Rouzaud1, Béatrice Regnault, Nicolas Da Rocha, Hélène Fontaine, Jérôme Le Pavec, Samuel Dolidon, Margaux Garzaro, Delphine Chrétien, Guillaume Morcrette, Thierry Jo Molina, Agnès Ferroni, Marianne Leruez-Ville, Olivier Lortholary2, Anne Jamet2, and Marc Eloit2Comments to Author 
Author affiliations: Institut Pasteur Pathogen Discovery Laboratory, Paris, France (P. Pérot, B. Regnault, N. Da Rocha, D. Chrétien, M. Eloit); The OIE Collaborating Center for the Detection and Identification in Humans of Emerging Animal Pathogens, Paris (P. Pérot, B. Regnault, N. Da Rocha, D. Chrétien, M. Eloit); Institut Imagine, Paris (J. Fourgeaud, M. Leruez-Ville); Université Paris Cité, Paris (J. Fourgeaud, A. Jamet); Necker-Enfants Malades Hospital, Paris (J. Fourgeaud, G. Morcrette, T.J. Molina, A. Ferroni, M. Leruez-Ville, A. Jamet); Hôpital Necker Enfants-Malades Centre d'Infectiologie Necker-Pasteur, Paris (C. Rouzaud, M. Garzaro, O. Lortholary); Groupe Hospitalier Paris Saint Joseph-Marie Lannelongue, Équipe Mobile de Microbiologie Clinique, Paris (C. Rouzaud); Hôpital Cochin Département d'Hépatologie-Addictologie, Paris (H. Fontaine); Université Paris–Sud, Paris (J. Le Pavec); Hôpital Marie Lannelongue Service de Pneumologie et Transplantation Pulmonaire, Le Plessis-Robinson, France (J. Le Pavec, S. Dolidon); Institut Necker Enfants Malades, Paris (A. Jamet); Ecole Nationale Vétérinaire d’Alfort, Maisons-Alfort, France (M. Eloit)

Main Article

Figure 3

Phylogenetic analysis of capsid protein sequences of human circovirus type 1 (HCirV-1) from a heart-lung transplant patient in France (red) and representative circovirus strains. Sequences were aligned with Multiple Alignment using Fast Fourier Transform (https://www.ebi.ac.uk/Tools/msa/mafft) under the L-INS-I parameter, and maximum-likelihood phylogenetic reconstruction was performed with PhyML implemented through the NGPhylogeny portal (https://ngphylogeny.fr). GenBank accession numbers for reference sequences are indicated, along with graphic representations of the animal of origin. Scale bar indicates the number of amino acid substitutions per site.

Figure 3. Phylogenetic analysis of capsid protein sequences of human circovirus type 1 (HCirV-1) from a heart-lung transplant patient in France (red) and representative circovirus strains. Sequences were aligned with Multiple Alignment using Fast Fourier Transform (https://www.ebi.ac.uk/Tools/msa/mafft) under the L-INS-I parameter, and maximum-likelihood phylogenetic reconstruction was performed with PhyML implemented through the NGPhylogeny portal (https://ngphylogeny.fr). GenBank accession numbers for reference sequences are indicated, along with graphic representations of the animal of origin. Scale bar indicates the number of amino acid substitutions per site.

Main Article

1These authors contributed equally to this article.

2These senior authors contributed equally to this article.

Page created: December 06, 2022
Page updated: January 23, 2023
Page reviewed: January 23, 2023
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