Circovirus Hepatitis Infection in Heart-Lung Transplant Patient, France
Philippe Pérot
1, Jacques Fourgeaud
1, Claire Rouzaud
1, Béatrice Regnault, Nicolas Da Rocha, Hélène Fontaine, Jérôme Le Pavec, Samuel Dolidon, Margaux Garzaro, Delphine Chrétien, Guillaume Morcrette, Thierry Jo Molina, Agnès Ferroni, Marianne Leruez-Ville, Olivier Lortholary
2, Anne Jamet
2, and Marc Eloit
2
Author affiliations: Institut Pasteur Pathogen Discovery Laboratory, Paris, France (P. Pérot, B. Regnault, N. Da Rocha, D. Chrétien, M. Eloit); The OIE Collaborating Center for the Detection and Identification in Humans of Emerging Animal Pathogens, Paris (P. Pérot, B. Regnault, N. Da Rocha, D. Chrétien, M. Eloit); Institut Imagine, Paris (J. Fourgeaud, M. Leruez-Ville); Université Paris Cité, Paris (J. Fourgeaud, A. Jamet); Necker-Enfants Malades Hospital, Paris (J. Fourgeaud, G. Morcrette, T.J. Molina, A. Ferroni, M. Leruez-Ville, A. Jamet); Hôpital Necker Enfants-Malades Centre d'Infectiologie Necker-Pasteur, Paris (C. Rouzaud, M. Garzaro, O. Lortholary); Groupe Hospitalier Paris Saint Joseph-Marie Lannelongue, Équipe Mobile de Microbiologie Clinique, Paris (C. Rouzaud); Hôpital Cochin Département d'Hépatologie-Addictologie, Paris (H. Fontaine); Université Paris–Sud, Paris (J. Le Pavec); Hôpital Marie Lannelongue Service de Pneumologie et Transplantation Pulmonaire, Le Plessis-Robinson, France (J. Le Pavec, S. Dolidon); Institut Necker Enfants Malades, Paris (A. Jamet); Ecole Nationale Vétérinaire d’Alfort, Maisons-Alfort, France (M. Eloit)
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Figure 4
Figure 4. In situ hybridization in liver section from a heart-lung transplant patient in France. Chromogenic in situ hybridization detected human circovirus type 1 mRNA (red staining) in hepatocytes nuclei and cytoplasm. Nuclei were counterstained with Harris hematoxylin and eosin stain; original magnification ×40.
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