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Volume 29, Number 8—August 2023
Research

Prospecting for Zoonotic Pathogens by Using Targeted DNA Enrichment

Egie E. Enabulele, Winka Le Clec’h, Emma K. Roberts, Cody W. Thompson, Molly M. McDonough, Adam W. Ferguson, Robert D. Bradley, Timothy J. C. Anderson, and Roy N. PlattComments to Author 
Author affiliations: Texas Biomedical Research Institute, San Antonio, Texas, USA (E.E. Enabulele, W. Le Clec’h, T.J.C. Anderson, R.N. Platt II); Texas Tech University, Lubbock, Texas, USA (E.K. Roberts, R.D. Bradley); University of Michigan, Ann Arbor, Michigan, USA (C.W. Thompson); Chicago State University, Chicago, Illinois, USA (M.M. McDonough); Field Museum of Natural History, Chicago (A.W. Ferguson)

Main Article

Figure 10

Sequence identity between enriched reads and baits in the probe panel used for targeting zoonotic pathogens in study of prospecting for zoonotic pathogens by using targeted DNA enrichment. Reads from each sample were classified against a database of target loci. Sequence identity between pathogen-derived reads and the most similar bait in the bait panel for all pathogens excluding Bartonella species (A) and for only Bartonella species (B). Bartonella was the most common pathogen in our samples, and the number of reads was biased toward a few individuals.

Figure 10. Sequence identity between enriched reads and baits in the probe panel used for targeting zoonotic pathogens in study of prospecting for zoonotic pathogens by using targeted DNA enrichment. Reads from each sample were classified against a database of target loci. Sequence identity between pathogen-derived reads and the most similar bait in the bait panel for all pathogens excluding Bartonella species (A) and for only Bartonella species (B). Bartonella was the most common pathogen in our samples, and the number of reads was biased toward a few individuals.

Main Article

Page created: June 07, 2023
Page updated: July 20, 2023
Page reviewed: July 20, 2023
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