Prospecting for Zoonotic Pathogens by Using Targeted DNA Enrichment
Egie E. Enabulele, Winka Le Clec’h, Emma K. Roberts, Cody W. Thompson, Molly M. McDonough, Adam W. Ferguson, Robert D. Bradley, Timothy J. C. Anderson, and Roy N. Platt
Author affiliations: Texas Biomedical Research Institute, San Antonio, Texas, USA (E.E. Enabulele, W. Le Clec’h, T.J.C. Anderson, R.N. Platt II); Texas Tech University, Lubbock, Texas, USA (E.K. Roberts, R.D. Bradley); University of Michigan, Ann Arbor, Michigan, USA (C.W. Thompson); Chicago State University, Chicago, Illinois, USA (M.M. McDonough); Field Museum of Natural History, Chicago (A.W. Ferguson)
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Figure 9
Figure 9. Genetic identification of mammal host from unenriched, mitochondrial reads in study of prospecting for zoonotic pathogens by using targeted DNA enrichment. Reads were compared with a database of mammalian mitochondria and assigned a taxonomic classification based on these results. A heatmap of the results shows the relative proportion of classified reads assigned to mammalian genera. Samples with <50 mitochondrial reads and single-read genera are not shown.
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