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Volume 29, Number 8—August 2023
Research

Prospecting for Zoonotic Pathogens by Using Targeted DNA Enrichment

Egie E. Enabulele, Winka Le Clec’h, Emma K. Roberts, Cody W. Thompson, Molly M. McDonough, Adam W. Ferguson, Robert D. Bradley, Timothy J. C. Anderson, and Roy N. PlattComments to Author 
Author affiliations: Texas Biomedical Research Institute, San Antonio, Texas, USA (E.E. Enabulele, W. Le Clec’h, T.J.C. Anderson, R.N. Platt II); Texas Tech University, Lubbock, Texas, USA (E.K. Roberts, R.D. Bradley); University of Michigan, Ann Arbor, Michigan, USA (C.W. Thompson); Chicago State University, Chicago, Illinois, USA (M.M. McDonough); Field Museum of Natural History, Chicago (A.W. Ferguson)

Main Article

Table 1

Zoonotic pathogens targeted for DNA enrichment in study of prospecting for zoonotic pathogens by using targeted DNA enrichment

Pathogen group Taxonomic level Focal pathogen Zoonoses
Anaplasma Genus Anaplasma phagocytophilum Anaplasmosis
Apicomplexa Phylum Plasmodium falciparum Malaria
Bacillus cereus group* Species group Bacillus anthracis Anthrax
Bartonella Genus Bartonella bacilliformis Cat-scratch fever
Borrelia Genus Borrelia burgdorferi Lyme disease
Burkholderia Genus Burkholderia mallei Glanders
Campylobacter Genus Campylobacter jejuni Campylobacteriosis
Cestoda Class Taenia multiceps Taeniasis
Chlamydia Genus Chlamydia trachomatis Chlamydia
Coxiella Genus Coxiella burnetii Q fever
Ehrlichia Genus Ehrlichia canis Ehrlichiosis
Eurotiales Order Talaromyces marneffei Talaromycosis
Francisella Genus Francisella tularensis Tularemia
Hexamitidae Family Giardia intestinalis Giardiasis
Kinetoplastea Class Leishmania major Leishmaniasis
Leptospira Genus Leptospira interrogans Leptospirosis
Listeria Genus Listeria monocytogenes Listeriaosis
Mycobacterium Genus Mycobacterium tuberculosis Tuberculosis
Nematodes (clade I) Phylum (clade) Trichinella spiralis Trichinosis
Nematodes (clade III) Phylum (clade) Brugia malayi Filariasis
Nematodes (clade IVa) Phylum (clade) Strongyloides stercoralis Strongyloidiasis
Nematodes (clade IVb) Phylum (clade) Steinernema carpocapsae None
Nematodes (clade V) Phylum (clade) Haemonchus contortus None
Onygenales Order Histoplasma capsulatum Histoplasmosis
Pasteurella Genus Pasteurella multocida Pasteurellosis
Rickettsia Genus Rickettsia rickettsii Typhus
Salmonella Genus Salmonella enterica Salmonellosis
Streptobacillus Genus Streptobacillus moniliformis Rat-bite fever
Trematoda Class Schistosoma mansoni Schistosomiasis
Tremellales Order Cryptococcus neoformans Cryptococcosis
Trypanosoma* Genus Trypanosoma cruzi Sleeping sickness
Yersinia Genus Yersinia pestis Plague

*Supplemented with additional probes/baits.

Main Article

Page created: June 07, 2023
Page updated: July 20, 2023
Page reviewed: July 20, 2023
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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