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Volume 30, Number 12—December 2024
Research

Dogs as Reservoirs for Leishmania donovani, Bihar, India, 2018–2022

Anurag Kumar Kushwaha1, Ashish Shukla1, Breanna M. Scorza, Rahul Chaubey, Dharmendra Kumar Maurya, Tulika Kumari Rai, Shyamali Yaduvanshi, Shweta Srivastava, Gaetano Oliva, Epke A. Le Rutte, Rajiv Kumar, Om Prakash Singh, Puja Tiwary, Shakti Kumar Singh, Scott A. Bernhardt, Phillip Lawyer, Edgar Rowton, Christine A. Petersen1Comments to Author , and Shyam Sundar1
Author affiliation: Banaras Hindu University, Varanasi, India (A.K. Kushwaha, A. Shukla, D.K. Maurya, T.K. Rai, S. Yaduvanshi, S. Srivastava, R. Kumar, O.P. Singh, P. Tiwary); University of Iowa, Iowa City, Iowa, USA (B.M. Scorza, C.A. Petersen); Kala-Azar Medical Research Center, Muzaffarpur, India (R. Chaubey, S. Sundar); University of Naples Federico II, Naples, Italy (G. Oliva), Swiss Tropical and Public Health Institute, Basel, Switzerland (E.A. Le Rutte); National Museum of Natural History, New Delhi, India (S.K. Singh); Utah State University, Logan, Utah, USA (S.A. Bernhardt); Walter Reed Army Institute for Research, Silver Spring, Maryland, USA (P. Lawyer, E. Rowton)

Main Article

Figure 2

Seropositivity among endemic dogs with clinical signs consistent with CanL from the Muzaffarpur district in a study of dogs as reservoirs for Leishmania donovani, Bihar, India, 2018–2022. A,C,E) Results from subclinical (healthy) dogs; B,D,F) results from dogs with >2 clinical signs of CanL. Percentage of positive (black) versus negative (white) results by kinetoplastid-targeted qPCR or by rK39 ELISA are shown. E,F) Percentage of dogs with single-positive or double-positive diagnostic status among subclinical dogs (E) and clinical dogs (F). Statistical significance between subclinical and clinical groups measured by Fisher exact test. CanL, canine leishmaniosis; qPCR, quantitative PCR; +, positive; −, negative.

Figure 2. Seropositivity among endemic dogs with clinical signs consistent with CanL from the Muzaffarpur district in a study of dogs as reservoirs for Leishmania donovani, Bihar, India, 2018–2022. A,C,E) Results from subclinical (healthy) dogs; B,D,F) results from dogs with >2 clinical signs of CanL. Percentage of positive (black) versus negative (white) results by kinetoplastid-targeted qPCR or by rK39 ELISA are shown. E,F) Percentage of dogs with single-positive or double-positive diagnostic status among subclinical dogs (E) and clinical dogs (F). Statistical significance between subclinical and clinical groups measured by Fisher exact test. CanL, canine leishmaniosis; qPCR, quantitative PCR; +, positive; −, negative.

Main Article

1These authors contributed equally to this article.

Page created: October 30, 2024
Page updated: November 26, 2024
Page reviewed: November 26, 2024
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