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Volume 30, Number 12—December 2024
Research

Dogs as Reservoirs for Leishmania donovani, Bihar, India, 2018–2022

Anurag Kumar Kushwaha1, Ashish Shukla1, Breanna M. Scorza, Rahul Chaubey, Dharmendra Kumar Maurya, Tulika Kumari Rai, Shyamali Yaduvanshi, Shweta Srivastava, Gaetano Oliva, Epke A. Le Rutte, Rajiv Kumar, Om Prakash Singh, Puja Tiwary, Shakti Kumar Singh, Scott A. Bernhardt, Phillip Lawyer, Edgar Rowton, Christine A. Petersen1Comments to Author , and Shyam Sundar1
Author affiliation: Banaras Hindu University, Varanasi, India (A.K. Kushwaha, A. Shukla, D.K. Maurya, T.K. Rai, S. Yaduvanshi, S. Srivastava, R. Kumar, O.P. Singh, P. Tiwary); University of Iowa, Iowa City, Iowa, USA (B.M. Scorza, C.A. Petersen); Kala-Azar Medical Research Center, Muzaffarpur, India (R. Chaubey, S. Sundar); University of Naples Federico II, Naples, Italy (G. Oliva), Swiss Tropical and Public Health Institute, Basel, Switzerland (E.A. Le Rutte); National Museum of Natural History, New Delhi, India (S.K. Singh); Utah State University, Logan, Utah, USA (S.A. Bernhardt); Walter Reed Army Institute for Research, Silver Spring, Maryland, USA (P. Lawyer, E. Rowton)

Main Article

Table

Canine diagnostic test outcomes and sand fly qPCR positivity after xenodiagnosis in a study of dogs as reservoirs for Leishmania donovani, Bihar, India, 2018–2022*

Clinical signs Diagnostic test results No. CanL-positive dogs/no. dogs
 No. qPCR-positive fed sand flies/no. dogs
Summer Rainy Winter Summer Rainy Winter
Total no. (%), n = 73
 NA
 16 (22)
 47 (64)
 10 (14)
16 (22)
 47 (64)
 10 (14)
No CanL clinical signs, n = 44
 qPCR–, ELISA– 7/9 17/30 5/5 0 5/2 1/1
qPCR+, ELISA– 0 2/30 0 0 0 0
qPCR–, ELISA+ 2/9 9/30 0 0 0 0
qPCR+, ELISA+
 0
 2/30
 0
0
 0
 0
CanL clinical signs, n = 29 qPCR–, ELISA– 2/7 0 3/5 0 0 9/2
qPCR+, ELISA– 0 2/17 0 0 0 0
qPCR–, ELISA+ 5/7 11/17 2/5 0 9/2 8/2
qPCR+, ELISA+ 0 4/17 0 0 0 0

*CanL, canine leishmaniosis; NA, not applicable; qPCR, quantitative PCR; +, positive; –, negative.

Main Article

1These authors contributed equally to this article.

Page created: October 30, 2024
Page updated: November 26, 2024
Page reviewed: November 26, 2024
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