Volume 30, Number 6—June 2024
Synopsis
Deciphering Unexpected Vascular Locations of Scedosporium spp. and Lomentospora prolificans Fungal Infections, France
Table 2
Clinical and radiologic characteristics of patients in study of unexpected vascular locations of Scedosporium spp. and Lomentospora prolificans fungal infections, France*
Variables |
SOS, n = 7 | Literature, n = 13 | Total, n = 20 | |
---|---|---|---|---|
Clinical manifestations at diagnosis | ||||
Fever | 6/7 (86) | 3/8 (38) | 9/15 (60) | |
Sepsis | 1/7 (14) | 2/13 (15) | 3/20 (15) | |
Thoracic or abdominal pain among aortitis | 2/5 (40) | 5/9 (56) | 7/14 (50) | |
Local inflammatory sign among peripheral arteritis |
0 |
2/4 (50) |
2/10 (20) |
|
Vascular involvement at scedosporiosis/lomentosporiosis diagnosis |
5/7 (71) |
5/13 (39) |
10/20 (50) |
|
Other infection locations | ||||
Pulmonary | 4/7 (57) | 5/13 (39) | 9/20 (45) | |
Central nervous system | 2/7 (29) | 3/13 (23) | 5/20 (25) | |
Cutaneous | 2/7 (29) | 2/13 (15) | 4/20 (20) | |
Osteoarticular | 3/7 (43) | 7/13 (54) | 10/20 (50) | |
Including spondylodiscitis | 1/3 (33) | 4/7 (57) | 5/10 (50) | |
Including contiguous localizations | 1/3 (33) | 6/7 (86) | 7/10 (70) | |
Endocarditis |
2/7 (29) |
2/13 (15) |
4/20 (20) |
|
Localization of vascular infection | ||||
Aortitis | 5/7 (71) | 9/13 (69) | 14/20 (70) | |
Including thoracic aortitis | 1/5 (20) | 4/8 (50) | 5/13 (39) | |
Including abdominal aortitis | 4/5 (80) | 4/8 (50) | 8/13 (62) | |
Peripheral arteritis | 6/7 (86) | 4/13 (31) | 10/20 (50) | |
Including iliac or femoral arteritis |
3/6 (50) |
1/4 (25) |
4/10 (40) |
|
Type of aortitis vascular impairment | ||||
Aneurysm | 1/4 (25) | 7/7 (100) | 8/11 (73) | |
With rupture | 1/1 (100) | 2/7 (29) | 3/8 (38) | |
Perivascular abscess | 1/4 (25) | 0 | 1/11 (9) | |
Isolated vascular thickening |
2/4 (50) |
0 |
2/11 (18) |
|
Type of peripheral arteritis vascular impairment | ||||
Aneurysm | 3/6 (50) | 3/4 (75) | 6/10 (60) | |
With rupture | 0 | 1/3 (33) | 1/6 (17) | |
Perivascular abscess | 1/6 (17) | 0 | 1/10 (10) | |
Septic thrombosis | 2/6 (33) | 1/4 (25) | 3/10 (30) | |
Isolated vascular thickening |
1/6 (17) |
0 |
1/10 (10) |
|
Vascular hypermetabolism on PET/CT |
3/3 (100) | 3/3 (100) | 6/6 (100) |
*Values are no./total no. analyzed (%). Denominators are different in some cases because of missing data. Patients had non–central nervous system vascular infections caused by Scedosporium spp. or Lomentospora prolificans; cases were obtained from the SOS and published literature. PET/CT, positron emission tomography/computed tomography; SOS, Scedosporiosis/lomentosporiosis Observational Study.
Page created: March 28, 2024
Page updated: May 22, 2024
Page reviewed: May 22, 2024
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