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Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released.

Volume 30, Number 7—July 2024
Research

Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Domestic Dairy Cattle and Cats, United States, 2024

Eric R. BurroughComments to Author , Drew R. Magstadt, Barbara Petersen, Simon J. Timmermans, Phillip C. Gauger, Jianqiang Zhang, Chris Siepker, Marta Mainenti, Ganwu Li, Alexis C. Thompson, Patrick J. Gorden, Paul J. Plummer, and Rodger Main
Author affiliations: Iowa State University College of Veterinary Medicine, Ames, Iowa, USA (E.R. Burrough, D.R. Magstadt, P.C. Gauger, J. Zhang, C. Siepker, M. Mainenti, G. Li, P.J. Gorden, P.J. Plummer, R. Main); Sunrise Veterinary Service PLLC, Amarillo, Texas, USA (B. Petersen); Veterinary Research & Consulting Services LLC, Hays, Kansas, USA (S.J. Timmermans); Texas A&M Veterinary Medical Diagnostic Laboratory, College Station, Texas, USA (A.C. Thompson)

Main Article

Table 1

Microscopic lesions observed in cattle in study of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b virus infection in domestic dairy cattle and cats, United States, 2024*

Case no. Animal US state Suppurative mastitis Hepatitis Abomasitis IAV-positive tissue†
1 Cow 1 Texas ++ + + Mammary gland
1 Cow 2 Texas ++ + ++ Mammary gland
3 Cow 1 Kansas NA + + NA
3 Cow 2 Kansas NA – + NA
4 Cow 1 Kansas NA – NA Lymph node
5 Cow 1 Kansas NA – – NA

*Avian influenza A(H5N1) virus was detected by using real-time reverse transcription PCR. IAV, influenza A virus; NA, not available; –, negative; +, scant lesions; ++, moderate lesions. †Determined by immunohistochemistry.

Main Article

Page created: April 29, 2024
Page updated: April 29, 2024
Page reviewed: April 29, 2024
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