Volume 30, Number 7—July 2024
Research
Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Domestic Dairy Cattle and Cats, United States, 2024
Eric R. Burrough
, Drew R. Magstadt, Barbara Petersen, Simon J. Timmermans, Phillip C. Gauger, Jianqiang Zhang, Chris Siepker, Marta Mainenti, Ganwu Li, Alexis C. Thompson, Patrick J. Gorden, Paul J. Plummer, and Rodger Main
, Drew R. Magstadt, Barbara Petersen, Simon J. Timmermans, Phillip C. Gauger, Jianqiang Zhang, Chris Siepker, Marta Mainenti, Ganwu Li, Alexis C. Thompson, Patrick J. Gorden, Paul J. Plummer, and Rodger Main
Table 1
Microscopic lesions observed in cattle in study of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b virus infection in domestic dairy cattle and cats, United States, 2024*
| Case no. | Animal | US state | Suppurative mastitis | Hepatitis | Abomasitis | IAV-positive tissue† |
|---|---|---|---|---|---|---|
| 1 | Cow 1 | Texas | ++ | + | + | Mammary gland |
| 1 | Cow 2 | Texas | ++ | + | ++ | Mammary gland |
| 3 | Cow 1 | Kansas | NA | + | + | NA |
| 3 | Cow 2 | Kansas | NA | – | + | NA |
| 4 | Cow 1 | Kansas | NA | – | NA | Lymph node |
| 5 | Cow 1 | Kansas | NA | – | – | NA |
*Avian influenza A(H5N1) virus was detected by using real-time reverse transcription PCR. IAV, influenza A virus; NA, not available; –, negative; +, scant lesions; ++, moderate lesions. †Determined by immunohistochemistry.
Page created: April 29, 2024
Page updated: June 22, 2024
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