Volume 30, Number 7—July 2024
Research
Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Domestic Dairy Cattle and Cats, United States, 2024
Table 3
Case no. | Animal | State | IAV PCR test | Ct values for IAV PCR |
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Milk | Mammary gland | Brain | Lung | Spleen | Lymph node | Ocular fluid | Rumen contents | ||||
1 |
Cow 1 |
Texas |
IAV screen | NA |
16.2 | NA |
≥40 | NA |
NA |
NA |
NA |
H5 subtype | 17.9 | NA | |||||||||
H5 2.3.4.4 |
17.8 |
NA |
|||||||||
1 |
Cow 2 |
Texas |
IAV screen | NA |
NA |
NA |
32.6 | NA |
NA |
NA |
NA |
H5 subtype | 36.0 | ||||||||||
H5 2.3.4.4 |
34.8 |
||||||||||
2 |
Cow 1 |
Texas |
IAV screen | 12.3 | NA |
NA |
NA |
NA |
NA |
NA |
NA |
H5 subtype | 18.8 | ||||||||||
H5 2.3.4.4 |
14.7 |
||||||||||
2 |
Cow 2 |
Texas |
IAV screen | 13.1 | NA |
NA |
NA |
NA |
NA |
NA |
NA |
H5 subtype | 17.6 | ||||||||||
H5 2.3.4.4 |
15.1 |
||||||||||
3 |
Cow 1 |
Kansas |
IAV screen | 15.2 | NA |
NA |
≥40 | ≥40 | ≥40 | 29.0 | 31.0 |
H5 subtype | 19.5 | NA | NA | NA | 31.2 | 32.7 | |||||
H5 2.3.4.4 |
17.1 |
NA |
NA |
NA |
30.9 |
32.2 |
|||||
3 |
Cow 2 |
Kansas |
IAV screen | NA |
NA |
NA |
≥40 | ≥40 | NA |
≥40 | ≥40 |
H5 subtype | NA | NA | NA | NA | |||||||
H5 2.3.4.4 |
NA |
NA |
NA |
NA |
|||||||
4 |
Cow 1 |
Kansas |
IAV screen | 16.9 | NA |
NA |
33.0 | ≥40 | 31.2 | ≥40 | 29.4 |
H5 subtype | 23.1 | ≥40 | NA | 38.0 | NA | 32.4 | |||||
H5 2.3.4.4 |
20.0 |
≥40 |
NA |
33.9 |
NA |
31.1 |
|||||
5 |
Cow 1 |
Kansas |
IAV screen | ≥40 | NA |
NA |
34.1 | 29.8 | NA |
NA |
NA |
H5 subtype | NA | 37.8 | 36.1 | ||||||||
H5 2.3.4.4 |
NA |
37.3 |
33.9 |
||||||||
6 |
Cat 1 |
Texas |
IAV screen | NA |
NA |
9.9 | 17.4 | NA |
NA |
NA |
NA |
H5 subtype | 10.7 | 16.5 | |||||||||
H5 2.3.4.4 |
11.9 |
18.0 |
|||||||||
6 | Cat 2 | Texas | IAV screen | NA | NA | 13.5 | 24.4 | NA | NA | NA | NA |
H5 subtype | 14.0 | 23.8 | |||||||||
H5 2.3.4.4 | 15.2 | 24.8 |
*Ct values were obtained by using real-time reverse transcription PCR tests for influenza A viruses, the H5 subtype, and H5 clade 2.3.4.4 viruses. Ct, cycle threshold; H5, hemagglutinin 5; IAV, influenza A virus; NA, not available.
Page created: April 29, 2024
Page updated: June 22, 2024
Page reviewed: June 22, 2024
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