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Volume 30, Number 7—July 2024
Research

Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Domestic Dairy Cattle and Cats, United States, 2024

Eric R. BurroughComments to Author , Drew R. Magstadt, Barbara Petersen, Simon J. Timmermans, Phillip C. Gauger, Jianqiang Zhang, Chris Siepker, Marta Mainenti, Ganwu Li, Alexis C. Thompson, Patrick J. Gorden, Paul J. Plummer, and Rodger Main
Author affiliations: Iowa State University College of Veterinary Medicine, Ames, Iowa, USA (E.R. Burrough, D.R. Magstadt, P.C. Gauger, J. Zhang, C. Siepker, M. Mainenti, G. Li, P.J. Gorden, P.J. Plummer, R. Main); Sunrise Veterinary Service PLLC, Amarillo, Texas, USA (B. Petersen); Veterinary Research & Consulting Services LLC, Hays, Kansas, USA (S.J. Timmermans); Texas A&M Veterinary Medical Diagnostic Laboratory, College Station, Texas, USA (A.C. Thompson)

Main Article

Table 2

Microscopic lesions observed in cats in study of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b virus infection in domestic dairy cattle and cats, United States, 2024*

Case no. Animal US state Encephalitis Retinitis Interstitial pneumonia Necrotizing myocarditis Vacuolar hepatopathy IAV-positive tissues†
6 Cat 1 Texas +++ – ++ ++ + Brain, lung, heart
6 Cat 2 Texas +++ ++ ++ ++ + Brain, lung, heart

*Avian influenza A(H5N1) virus was detected by using real-time reverse transcription PCR. IAV, influenza A virus; –, negative; +, scant lesions; ++, moderate lesions; +++, severe lesions. †Determined by immunohistochemistry.

Main Article

Page created: April 29, 2024
Page updated: June 22, 2024
Page reviewed: June 22, 2024
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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