Trichuriasis in Human Patients from Côte d’Ivoire Caused by Novel Species Trichuris incognita with Low Sensitivity to Albendazole/Ivermectin Combination Treatment
Abhinaya Venkatesan
1, Rebecca Chen, Max Bär, Pierre H.H. Schneeberger, Brenna Reimer, Eveline Hürlimann, Jean T. Coulibaly, Said M. Ali, Somphou Sayasone, John Soghigian, Jennifer Keiser, and John Stuart Gilleard
Author affiliation: University of Calgary, Calgary, Alberta, Canada (A. Venkatesan, R. Chen, B. Reimer, J. Soghigian, J.S. Gilleard); Swiss Tropical and Public Health Institute, Allschwil, Switzerland (M. Bär, P.H.H. Schneeberger, E. Hürlimann, J. Keiser); University of Basel, Basel, Switzerland (M. Bär, P.H.H. Schneeberger, E. Hürlimann, J. Keiser); Université Félix Hophouët-Boigny, Abidjan, Côte d’Ivoire (J.T. Coulibaly); Public Health Laboratory Ivo de Carneri, Chake Chake, Pemba Island, Tanzania (S.M. Ali); Lao Tropical and Public Health Institute, Vientiane, Laos (S. Sayasone)
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Figure 5
Figure 5. Schematic of phylogenetic relationships of Trichuris spp. infecting humans and nonhuman primates adapted from previously published studies. Relationships are indicated for the ribosomal ITS1-5.8S-ITS2 region (A) and the mitochondrial genome (B). Two major clades of Trichuris in the ribosomal DNA and mitochondrial DNA phylogenies infected both humans and nonhuman primates. Yellow circle indicates T. trichiura from Pemba Island, blue indicates T. trichiura from Laos, and red circle indicates T. incognita from Côte d’Ivoire. Pig-derived T. suis is also included in the tree as a reference. Star indicates Trichinella spiralis, used as an outgroup.
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