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Volume 31, Number 3—March 2025
Research

High Prevalence of atpE Mutations in Bedaquiline-Resistant Mycobacterium tuberculosis Isolates, Russia

Danila ZimenkovComments to Author , Anastasia Ushtanit, Elizaveta Gordeeva, Elena Guselnikova, Yakov Schwartz, and Natalia Stavitskaya
Author affiliation: Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia (D. Zimenkov, A. Ushtanit); Federal State Budgetary Institution Novosibirsk TB Research Institute, Ministry of Health, Novosibirsk, Russia (E. Gordeeva, E. Guselnikova, Y. Schwartz, N. Stavitskaya)

Main Article

Figure 2

Mapping of the candidate substitution Val165Ile in AtpB on the atomic model of Mycobacterium tuberculosis ATP synthase (PDB: 8J0S) in study of high prevalence of atpE mutations in bedaquiline-resistant M. tuberculosis isolates, Russia. Identical c subunits of the rotor (encoded by the atpE gene) are shown with distinct colors.

Figure 2. Mapping of the candidate substitution Val165Ile in AtpB on the atomic model of Mycobacterium tuberculosis ATP synthase (PDB: 8J0S) in study of high prevalence of atpE mutations in bedaquiline-resistant M. tuberculosis isolates, Russia. Identical c subunits of the rotor (encoded by the atpE gene) are shown with distinct colors.

Main Article

Page created: January 06, 2025
Page updated: February 28, 2025
Page reviewed: February 28, 2025
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