Volume 31, Number 4—April 2025
Research
Detection and Decontamination of Chronic Wasting Disease Prions during Venison Processing
Figure 7

Figure 7. Results of real-time quaking-induced conversion assays conducted on meat grinder swab samples in study of detection and decontamination of chronic wasting disease prions during venison processing. Swab samples were taken after grinder parts were soaked in 1 of 4 decontaminants (after chronic wasting disease–positive muscle was passed through each): dish soap (top row), Dawn brand (Procter & Gamble, https://dawn-dish.com); Virkon-S (second row), 2% potassium peroxymonosulfate (Lanxess AG, https://lanxess.com); and bleach, 10% vol/vol (7,500 ppm) (third row) and 40% vol/vol (30,000 ppm) (bottom row) commercial bleach solutions (7.5% sodium hypochlorite; The Clorox Company, https://www.clorox.com). A) Rate of amyloid formation; B) maxpoint ratio (ratio of the maximum value to the initial reading); C) maximum slope. Each dot is an average of a single biological replicate (consisting of 8 technical replicates). PC, plate cutter; SRT, screw ring threads; WS, worm spindle.