Table 6

Volume 32, Number 4—April 2026

Transmissibility and Disease Progression of Asymptomatic Mycobacterium tuberculosis Infection, Lima, Peru

Ruitong Wang, Chuan-Chin Huang, Mercedes C. Becerra, Roger I. Calderon, Carmen C. Contreras, Jerome T. Galea, Judith Jimenez, Leonid Lecca, Rosa M. Yataco, Zibiao Zhang, and Megan B. Murray

Author affiliation: Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA (R. Wang, M.B. Murray); Harvard Medical School, Boston (C.-C. Huang, M.C. Becerra, L. Lecca, M.B. Murray); Brigham and Women’s Hospital, Boston (C.-C. Huang, Z. Zhang, M.B. Murray); Advanced Research and Health, Lima, Peru (R.I. Calderon); Universidad de San Martin de Porres, Lima (R.I. Calderon); Partners In Health—Socios En Salud Sucursal Peru, Lima (C.C. Contreras, J. Jimenez, L. Lecca, R.M. Yataco); University of South Florida, Tampa, Florida, USA (J.T. Galea)

Main Article

Association between characteristics of asymptomatic index patients and risk for Mycobacterium tuberculosis infection at 6-month follow-up of all household contacts in study of transmissibility of asymptomatic M. tuberculosis, Lima, Peru*

Characteristic	No. (%) uninfected contacts	No. (%) infected contacts	Odds ratio (95%CI)	p value
Age group, y, n = 230
16–30	92 (50.5)	26 (54.2)	Referent	Referent
31–45	20 (11.0)	6 (12.5)	1.08 (0.44–2.68)	0.87
46–60	12 (6.59)	10 (20.8)	3.00 (1.41–6.37)	0.004
≥61	58 (31.9)	6 (12.5)	0.40 (0.19–0.89)	0.02
Sex, n = 230
M	143 (78.6)	42 (87.5)	Referent	Referent
F	39 (21.4)	6 (12.5)	0.48 (0.17–1.37)	0.17
HIV status, n = 230
Negative	131 (72.0)	42 (87.5)	Referent	Referent
Positive	51 (28.0)	6 (12.5)	0.37 (0.19–0.74)	0.005
Smoking status, n = 230
Nonsmoker	171 (94.5)	45 (93.8)	Referent	Referent
Smoker	10 (5.52)	3 (6.25)	1.02 (0.40–2.60)	0.85
SES, n = 222†
Low	58 (32.6)	10 (22.7)	Referent	Referent
Medium	105 (59.0)	23 (52.3)	1.36 (0.61–3.03)	0.46
High	15 (8.43)	11 (25.0)	4.30 (1.49–12.4)	0.007
Employment status, n = 228
Stay at home	121 (67.2)	37 (77.1)	Referent	Referent
Work outside	59 (32.8)	11 (22.9)	0.54 (0.26–1.14)	0.11
Alcohol consumption, n = 208
Drinker	41 (24.8)	17 (39.5)	Referent	Referent
Nondrinker	124 (75.2)	26 (60.5)	0.53 (0.27–1.03)	0.06
Diabetes, n = 230
No	179 (98.4)	47 (97.9)	Referent	Referent
Yes	3 (1.65)	1 (2.08)	1.21 (0.12–11.9)	0.87

*Results of univariate analysis. SES, socioeconomic status. †We created a continuous variable to capture summarize household-level socioeconomic status by including variables on housing quality, water supply and sanitation in a principal component analysis. The continuous SES score was categorized into tertiles corresponding to relative low, middle, and upper SES.

Main Article

Page created: March 10, 2026

Page updated: April 15, 2026

Page reviewed: April 15, 2026

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