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Volume 32, Number 6—June 2026

Research

Role of Households with Children in Community Spread of Multidrug-Resistant Enterobacterales, St. Louis, Missouri, USA

Barrett Breeze1, Ahmed Babiker1, Sreenivas Konda, Alaina L. Robinson, Stefan J. Green, Catherine C. Babbs, Federico Cunha, Katherine Y. Shen, India Shepherd Hammond, Stephanie A. Fritz, and Latania K. LoganComments to Author 
Author affiliation: Emory University School of Medicine, Atlanta, Georgia, USA (B. Breeze, C.C. Babbs, F. Cunha, K.Y. Shen, I.S. Hammond, L.K. Logan); Rush University Medical Center, Chicago, Illinois, USA (A. Babiker, S.J. Green); The University of Chicago, Chicago (S. Konda); Washington University School of Medicine, St. Louis, Missouri, USA (A.L. Robinson, S.A. Fritz); Children’s Healthcare of Atlanta, Atlanta, Georgia, USA (L.K. Logan)

Main Article

Table 3

Klebsiella pneumoniae characteristics by isolate source in study of role of households with children in community spread of multidrug-resistant Enterobacterales, St. Louis, Missouri, USA*

Characteristic Total, n = 10 Environmental source, n = 7 Human source, n = 3
MLST
Unknown 2 (20) 2 (29) 0
1380 1 (10) 1 (14) 0
20 1 (10) 1 (14) 0
29 2 (20) 1 (14) 1 (33)
461 1 (10) 1 (14) 0
466 1 (10) 1 (14) 0
678
 2 (20)
 0
 2 (67)
Median AMR gene count per isolate (IQR)
 5 (4.25–5)
 5 (3.5–5)
 5 (5–5.5)
AMR resistance determinants
β-lactam AMR determinants 10 (100) 32 (100) 15 (100)
blaSHV, unspecified 2 (20) 1 (14) 1 (33)
blaSHV-1 1 (10) 1 (14) 0
blaSHV-187 1 (10) 1 (14) 0
blaSHV-26 1 (10) 1 (14) 0
blaSHV-33 1 (10) 1 (14) 0
blaSHV-36 2 (20) 2 (29) 0
blaSHV-41 2 (20) 0 2 (67)
blaTEM-10 2 (20) 1 (14) 1 (33)
Fosfomycin AMR determinants 10 (100) 7 (100) 3 (100)
fosA 6 (60) 3 (43) 3 (100)
fosA10 4 (40) 4 (57) 0
Multiclass AMR determinants
emrD 10 (100) 7 (100) 3 (100)
Phenicol/quinolone AMR determinants 7 (70) 4 (57) 3 (100)
oqxA 3 (30) 2 (29) 1 (33)
oqxA3 1 (10) 1 (14) 0
oqxA10 3 (30) 1 (14) 2 (67)
oqxB 2 (20) 0 2 (67)
oqxB19 2 (20) 2 (29) 0
oqxB25 3 (30) 2 (29) 1 (33)
Trimethoprim AMR determinants 1 (10) 1 (14) 0
dfrA50
 1 (10)
 1 (14)
 0
Median plasmid count per isolate (IQR)
 3.5 (3–4.75)
 4 (3.5–5)
 3 (2–3)
Plasmids
Col440I 5 (50) 5 (71) 0
Col440II 3 (30) 3 (43) 0
IncFIB(K) 10 (100) 7 (100) 3 (100)
IncFIB(Mar) 1 (10) 1 (14) 0
IncFIB(pKPHS1) 1 (10) 1 (14) 0
IncFIB(pQil) 1 (10) 1 (14) 0
IncFII 3 (30) 1 (14) 2 (67)
IncFII(K) 8 (80) 6 (86) 2 (67)
IncFII(Yp) 1 (10) 1 (14) 0
IncHI1B 1 (10) 1 (14) 0
IncR 2 (20) 2 (29) 0
IncX5 1 (10) 1 (14) 0
repA 2 (20) 1 (14) 0

*Values are no. (%) except as indicated. AMR, antimicrobial resistance; IQR, interquartile range; MLST, multilocus sequence type.

Main Article

1These first authors contributed equally to this article.

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Page updated: May 20, 2026
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