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Volume 23, Number 2—February 2017


Swine Influenza Virus (H1N2) Characterization and Transmission in Ferrets, Chile

Nicolás Bravo-Vasquez1, Erik A. Karlsson1, Pedro Jimenez-Bluhm, Victoria Meliopoulos, Bryan Kaplan, Shauna Marvin, Valerie Cortez, Pamela Freiden, Melinda A. Beck, and Stacey Schultz-Cherry2Comments to Author 
Author affiliations: University of Chile, Santiago, Chile (N. Bravo-Vasquez, C. Hamilton-West); St. Jude Children’s Research Hospital, Memphis, Tennessee, USA (E.A. Karlsson, P. Jimenez-Bluhm, V. Meliopoulos, B. Kaplan, S. Marvin, V. Cortez, P. Freiden, S. Schultz-Cherry); University of North Carolina, Chapel Hill, North Carolina, USA (M.A. Beck)

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Antigenic characteristics of swine influenza virus (H1N2) from Chile and control viruses*

Virus Subtype Major clade Subclade Ferret antiserum results
MEM/87 sw/Chile sw/IA sw/NC sw/IT CA/09
MEM/87 hsH1N1 North America δ 640 < < < < <
sw/Chile swH1N2 North America δ < 640 < < < <
sw/Iowa swH1N2 North America δ1 < < 320 < < <
sw/NC swH1N1 North America γ2 < < < 80 < 80
sw/It swH1N1 Eurasian - < < < < 320 40
CA/09 pH1N1 North America pdm-like < < < < < 320
sw/In swH1N2 North America β < < < 320 160 40

*< refers to titers being below the minimum detectable hemagglutinin inhibition titer of 1:10. CA/09, A/California/04/2009; hs, human seasonal; MEM/87, A/Memphis/3/1987; pdm, pandemic; pH1N1, influenza A(H1N1)pdm09 virus; sw, swine; sw/Chile, A/swine/Chile/YA026/2014; sw/IA, A/swine/Iowa/13-1015/2010; sw/IN, A/swine/Indiana/26-0818/2011; sw/IT, A/swine/Italy/1310-2/1995; sw/NC, A/swine/North Carolina/18161/2002.

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1These first authors contributed equally to this article.

2These senior authors contributed equally to this article.