Antimicrobial Resistance in Invasive Bacterial Infections in Hospitalized Children, Cambodia, 2007–2016
, Junko Takata, Thyl Miliya, Yoel Lubell, Sona Soeng, Poda Sar, Kolthida Rith, Gregor McKellar, Vanaporn Wuthiekanun, Erin McGonagle, Nicole Stoesser, Catrin E. Moore, Christopher M. Parry, Claudia Turner, Nicholas P.J. Day, Ben S. Cooper, and Paul Turner
Author affiliations: University of Oxford, Oxford, UK (A. Fox-Lewis, J. Takata, Y. Lubell, N. Stoesser, C.E. Moore, C. Turner, N.P.J. Day, B.S. Cooper, P. Turner); Angkor Hospital for Children, Siem Reap, Cambodia (A. Fox-Lewis, T. Miliya, S. Soeng, P. Sar, K. Rith, G. McKellar, C. Turner, P. Turner); Cambodia-Oxford Medical Research Unit, Siem Reap (A. Fox-Lewis, T. Miliya, S. Soeng, P. Sar, K. Rith, C. Turner, P. Turner); Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand (Y. Lubell, V. Wuthiekanun, C.E. Moore, N.P.J. Day, B.S. Cooper); University of Colorado, Aurora, Colorado, USA (E. McGonagle); Liverpool School of Tropical Medicine, Liverpool, UK (C.M. Parry); Nagasaki University, Nagasaki, Japan (C.M. Parry)
Figure 1. Antimicrobial resistance time trends, shown as proportion of resistant isolates from community-acquired and hospital-acquired infections, by year of isolation, in children at Angkor Hospital for Children, Siem Reap, Cambodia, 2007–2016. A) Klebsiella pneumoniae ampicillin–gentamicin resistance; B) K. pneumoniae third-generation cephalosporin resistance; C) K. pneumoniae multidrug resistance; D) Escherichia coli ampicillin–gentamicin resistance; E) E. coli third-generation cephalosporin resistance; F) E. coli multidrug resistance; G) Salmonella enterica serotype Typhi fluoroquinolone resistance; H) Staphylococcus aureus methicillin resistance; I) Streptococcus pneumoniae penicillin resistance. Isolates were defined as hospital-acquired if taken >48 hours after patient admission. Error bars indicate 95% CIs.
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