Volume 24, Number 5—May 2018
Synopsis
Antimicrobial Resistance in Invasive Bacterial Infections in Hospitalized Children, Cambodia, 2007–2016
Table 4
Logistic regression analysis of resistance trends for the gram-negative Global Antimicrobial Resistance Surveillance System pathogen Salmonella enterica serovar Typhi isolated from children at Angkor Hospital for Children, Siem Reap, Cambodia, 2007–2016*
Resistance type, predictor variable |
Univariable analysis |
Multivariable analysis |
|||
OR (95% CI) |
p value |
OR (95% CI) |
p value |
||
Fluoroquinolone | |||||
Year of isolation | |||||
2007–2008 | Ref | Ref | Ref | Ref | |
2009–2010 | 2.05 (0.47–10.51) | 0.345 | 1.85 (0.42–9.59) | 0.422 | |
2011–2012 | 2.97 (0.82–10.37) | 0.085 | 3.05 (0.83–10.74) | 0.080 | |
2013–2014 | 4.03 × 107 (6.26 × 10−45–∞) | 0.992 | 3.47 × 107 (9.49 × 10−44–∞) | 0.992 | |
2015–2016 | 4.03 × 107 (1.11 × 10−43–∞) | 0.992 | 4.14 × 107 (6.26 × 10−43–∞) | 0.991 | |
Patient age, y | |||||
>5 | Ref | Ref | Ref | Ref | |
<5 |
4.48 (0.87–82.12) |
0.151 |
4.57 (0.87–84.30) |
0.150 |
|
Multidrug | |||||
Year of isolation | |||||
2007–2008 | Ref | Ref | Ref | Ref | |
2009–2010 | 1.57 (0.56–4.58) | 0.395 | 1.45 (0.50–4.29) | 0.491 | |
2011–2012 | 4.32 (1.64–11.44) | 0.003 | 4.55 (1.71–12.17) | 0.002 | |
2013–2014 | 2.26 (0.72–7.92) | 0.175 | 2.08 (0.65–7.41) | 0.228 | |
2015–2016 | 0.91 (0.33–2.46) | 0.850 | 0.95 (0.34–2.62) | 0.927 | |
Patient age, y | |||||
>5 | Ref | Ref | Ref | Ref | |
<5 | 2.94 (1.22–8.79) | 0.029 | 3.16 (1.28- 9.57) | 0.022 |
*OR, odds ratio; ref, referent.