Antimicrobial Resistance in Invasive Bacterial Infections in Hospitalized Children, Cambodia, 2007–2016
Andrew Fox-Lewis
, Junko Takata, Thyl Miliya, Yoel Lubell, Sona Soeng, Poda Sar, Kolthida Rith, Gregor McKellar, Vanaporn Wuthiekanun, Erin McGonagle, Nicole Stoesser, Catrin E. Moore, Christopher M. Parry, Claudia Turner, Nicholas P.J. Day, Ben S. Cooper, and Paul Turner
Author affiliations: University of Oxford, Oxford, UK (A. Fox-Lewis, J. Takata, Y. Lubell, N. Stoesser, C.E. Moore, C. Turner, N.P.J. Day, B.S. Cooper, P. Turner); Angkor Hospital for Children, Siem Reap, Cambodia (A. Fox-Lewis, T. Miliya, S. Soeng, P. Sar, K. Rith, G. McKellar, C. Turner, P. Turner); Cambodia-Oxford Medical Research Unit, Siem Reap (A. Fox-Lewis, T. Miliya, S. Soeng, P. Sar, K. Rith, C. Turner, P. Turner); Mahidol-Oxford Tropical Medicine Research Unit, Bangkok, Thailand (Y. Lubell, V. Wuthiekanun, C.E. Moore, N.P.J. Day, B.S. Cooper); University of Colorado, Aurora, Colorado, USA (E. McGonagle); Liverpool School of Tropical Medicine, Liverpool, UK (C.M. Parry); Nagasaki University, Nagasaki, Japan (C.M. Parry)
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Figure 2
Figure 2. Antimicrobial resistance age trends, shown as proportion of resistant isolates from community-acquired and hospital-acquired infections, by patient age group, in children at Angkor Hospital for Children, Siem Reap, Cambodia, 2007–2016. A) Klebsiella pneumoniae third-generation cephalosporin resistance; B) Escherichia coli third-generation cephalosporin resistance; C) Salmonella enterica serotype Typhi multidrug resistance; D) Streptococcus pneumoniae penicillin resistance. Ages have been grouped into neonate (0–28 d) versus nonneonate (>29 d) or <5 years versus >5 y, as appropriate for the organism. Isolates were defined as hospital-acquired if taken >48 hours after admission. Error bars indicate 95% CIs.
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