Volume 25, Number 1—January 2019
Research
Variable Protease-Sensitive Prionopathy Transmission to Bank Voles
Romolo Nonno1, Silvio Notari1, Michele Angelo Di Bari, Ignazio Cali, Laura Pirisinu, Claudia d’Agostino, Laura Cracco, Diane Kofskey, Ilaria Vanni, Jody Lavrich, Piero Parchi, Umberto Agrimi, and Pierluigi Gambetti
Table 2
Itemized VPSPr transmission features in bv109I at first passage, by phenotype*
| Genotype |
T1 | T2 | T3 | Attack rate for all phenotypes, % |
|||||
|---|---|---|---|---|---|---|---|---|---|
| Prevalence, % |
Survival time, dpi ± SD |
Prevalence, % |
Survival time, dpi ± SD |
Prevalence, % |
Survival time, dpi ± SD |
||||
| MM | 5 | 901 | 5 | 839 | 25 | 413 ± 102† | 35 | ||
| MV | 29.5 | 458 ± 137† | 13.6 | 872 ± 110† | 2.3 | 554 | 45.5 | ||
| VV | 0 | NA | 0 | NA | 11.1 | 596, 535 | 11.1 | ||
| All affected genotypes | 11.5‡ | 490 ± 177† | 6.2‡ | 867 ± 101† | 12.8‡ | 469 ± 110† | 30.5‡ | ||
*bv, bank voles; dpi: days postinoculation; VPSPr, variably protease-sensitive prionopathy.
†Weighted average ± SD.
‡Unweighted average.
1These authors contributed equally to this article.
Page created: December 18, 2018
Page updated: December 18, 2018
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