Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 25, Number 1—January 2019

Variable Protease-Sensitive Prionopathy Transmission to Bank Voles

Romolo Nonno1, Silvio Notari1, Michele Angelo Di Bari, Ignazio Cali, Laura Pirisinu, Claudia d’Agostino, Laura Cracco, Diane Kofskey, Ilaria Vanni, Jody Lavrich, Piero Parchi, Umberto Agrimi, and Pierluigi GambettiComments to Author 
Author affiliations: Istituto Superiore di Sanità, Rome, Italy (R. Nonno, M.A. Di Bari, L. Pirisinu, C. d’Agostino, I. Vanni, U. Agrimi); Case Western Reserve University, Cleveland, Ohio, USA (S. Notari, I. Cali, L. Cracco, D. Kofskey, J. Lavrich, P. Gambetti); University of Bologna, Bologna, Italy (P. Parchi); Istituto delle Scienze Neurologiche di Bologna, Bologna (P. Parchi)

Main Article

Table 2

Itemized VPSPr transmission features in bv109I at first passage, by phenotype*

T3 Attack rate for all phenotypes, %
Prevalence, %
Survival time, dpi ± SD
Prevalence, %
Survival time, dpi ± SD
Prevalence, %
Survival time, dpi ± SD
MM 5 901 5 839 25 413 ± 102† 35
MV 29.5 458 ± 137† 13.6 872 ± 110† 2.3 554 45.5
VV 0 NA 0 NA 11.1 596, 535 11.1
All affected genotypes 11.5‡ 490 ± 177† 6.2‡ 867 ± 101† 12.8‡ 469 ± 110† 30.5‡

*bv, bank voles; dpi: days postinoculation; VPSPr, variably protease-sensitive prionopathy.
†Weighted average ± SD.
‡Unweighted average.

Main Article

1These authors contributed equally to this article.

Page created: December 18, 2018
Page updated: December 18, 2018
Page reviewed: December 18, 2018
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.