Coronavirus Antibody Responses before COVID-19 Pandemic, Africa and Thailand
Yifan Li, Mélanie Merbah, Suzanne Wollen-Roberts, Bradley Beckman, Thembi Mdluli, Isabella Swafford, Sandra V. Mayer, Jocelyn King, Courtney Corbitt, Jeffrey R. Currier, Heather Liu, Allahna Esber, Suteeraporn Pinyakorn, Ajay Parikh, Leilani V. Francisco, Nittaya Phanuphak, Jonah Maswai, John Owuoth, Hannah Kibuuka, Michael Iroezindu, Emmanuel Bahemana, Sandhya Vasan, Julie A. Ake, Kayvon Modjarrad, Gregory Gromowski, Dominic Paquin-Proulx, and Morgane Rolland
Author affiliations: Walter Reed Army Institute of Research, Silver Spring, Maryland, USA (Y. Li, M. Merbah, S. Wollen-Roberts, B. Beckman, T. Mdluli, I. Swafford, S.V. Mayer, J. King, C. Corbitt, H. Liu, A. Esber, S. Pinyakorn, A. Parikh, L.V. Francisco, S. Vasan, J.A. Ake, K. Modjarrad, G. Gromowski, D. Paquin-Proulx, M. Rolland); Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, Maryland, USA (Y. Li, M. Merbah, S. Wollen-Roberts, B. Beckman, T. Mdluli, I. Swafford, H. Liu, A. Esber, S. Pinyakorn, A. Parikh, L.V. Francisco, S. Vasan, D. Paquin-Proulx, M. Rolland); Institute of HIV Research and Innovation, Bangkok, Thailand (N. Phanuphak); HJF Medical Research International, Kericho, Kenya (J. Maswai, J. Owuoth, M. Iroezindu, E. Bahemana); Makerere University Walter Reed Project, Kampala, Uganda (H. Kibuuka)
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Figure 6
Figure 6. Violin plots of signal-to-noise ratio comparing SARS-CoV-2 IgG responses in serum and plasma samples before COVID-19 pandemic, Thailand and Africa. Dotted line indicates signal-to-noise ratio cutoff. Results show higher SARS-CoV-2 responses in participants from Africa than in participants from Thailand. Significance was determined by Wilcoxon rank-sum test. KE, Kenya; N, nucleocapsid; NG, Nigeria; RBD, receptor-binding domain; S1, subunit 1; S2, subunit 2; TH, Thailand; TZ, Tanzania; UG, Uganda.
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