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Volume 29, Number 4—April 2023
Research

Adeno-Associated Virus 2 and Human Adenovirus F41 in Wastewater during Outbreak of Severe Acute Hepatitis in Children, Ireland

Niamh A. Martin, Gabriel Gonzalez, Liam J. Reynolds, Charlene Bennett, Christine Campbell, Tristan M. Nolan, Alannah Byrne, Sanne Fennema, Niamh Holohan, Sailusha Ratnam Kuntamukkula, Natasha Sarwar, Laura Sala-Comorera, Jonathan Dean, Jose Maria Urtasun-Elizari, Daniel Hare, Emer Liddy, Eadaoin Joyce, John J. O’Sullivan, John M. Cuddihy, Angeline M. McIntyre, Eve P. Robinson, Darren Dahly, Nicola F. Fletcher, Suzanne Cotter, Emer Fitzpatrick, Michael J. Carr, Cillian F. De Gascun, and Wim G. MeijerComments to Author 
Author affiliations: University College Dublin, Dublin, Ireland (N.A. Martin, G. Gonzalez, L.J. Reynolds, C. Bennett, C. Campbell, T.M. Nolan, A. Byrne, S. Fennema, N. Holohan, S.R. Kuntamukkula, N. Sarwar, L. Sala-Comorera, J. Dean, J.M. Urtasun-Elizari, D. Hare, J.J. O’Sullivan, N.F. Fletcher, M.J. Carr, C.F. De Gascun, W.G. Meijer); Hokkaido University, Sapporo, Japan (G. Gonzalez, M.J. Carr); Health Protection Surveillance Centre, Dublin, Ireland (E. Liddy, J.M. Cuddihy, A.M McIntyre, E.P. Robinson, S. Cotter); Irish Water, Dublin, Ireland (E. Joyce); University College Cork, Cork, Ireland (D. Dahly); Children’s Health Ireland at Crumlin, Crumlin, Ireland (E. Fitzpatrick)

Main Article

Figure 2

Scatterplots of Spearman correlation (rs) analysis between HAdV-F, AAV2, and SARS-CoV-2 detected in wastewater samples during outbreak of SAHUE in children, Ireland. Plots depict Spearman correlations between the log10 transformed daily HAdV viral load and AAV2 VP1 (A), AAV2 NSP (B), and SARS-CoV-2 N1 (C) in wastewater. AAV2, adeno-associated virus type 2; GC, genome copies; HAdV-F, human adenovirus type F; N1, nucleocapsid protein 1; NSP, nonstructural protein; SAHUE, severe acute hepatitis of unknown etiology.

Figure 2. Scatterplots of Spearman correlation (rs) analysis between HAdV-F, AAV2, and SARS-CoV-2 detected in wastewater samples during outbreak of SAHUE in children, Ireland. Plots depict Spearman correlations between the log10 transformed daily HAdV viral load and AAV2 VP1 (A), AAV2 NSP (B), and SARS-CoV-2 N1 (C) in wastewater. AAV2, adeno-associated virus type 2; GC, genome copies; HAdV-F, human adenovirus type F; N1, nucleocapsid protein 1; NSP, nonstructural protein; SAHUE, severe acute hepatitis of unknown etiology.

Main Article

Page created: January 24, 2023
Page updated: March 20, 2023
Page reviewed: March 20, 2023
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