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Volume 30, Number 8—August 2024
Synopsis

Outbreak of Intermediate Species Leptospira venezuelensis Spread by Rodents to Cows and Humans in L. interrogans–Endemic Region, Venezuela

Lizeth Caraballo, Yaritza Rangel, Armando Reyna-Bello1, Mariana Muñoz, Roque Figueroa-Espinosa2, Carlos E. Sanz-Rodriguez3, Elba Guerrero, Carmen Luisa Loureiro, Qingyun Liu4, and Howard E. TakiffComments to Author 
Author affiliations: Instituto Venezolano de Investigaciones Científicas, Caracas, Venezuela (L. Caraballo, Y. Rangel, M. Muñoz, R. Figueroa-Espinosa, C.E. Sanz-Rodriguez, E. Guerrero, C.L. Loureiro, H.E. Takiff); Universidad Nacional Experimental Simón Rodríguez, Caracas (A. Reyna-Bello); Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA (Q. Liu)

Main Article

Table 2

Analysis of blood and urine specimens from cows in study of outbreak of intermediate species Leptospira venezuelensis spread by rodents to cows and humans in L. interrogans–endemic region, Venezuela*

Cow no. rrs PCR
 lipL32 PCR
 Serology
 Cultures
 Sequenced species†
Blood Urine Blood Urine MAT titer Serovar Blood Urine
1 + – – – Negative NA + – L. venezuelensis
2 – – – – Negative NA – – NA
3 – + – – 1:800 L. wolffii – + L. venezuelensis
4 – – – – Negative NA – – NA
5 – + – + 1:400 L. hebdomadis – + L. interrogans
6 – – – – Negative NA – – NA
7 – + – – 1:800 L. wolffii – + L. venezuelensis
8 + – + – Negative NA + – L. interrogans
9 – + – + 1:400 L. mini – + L. interrogans
10 – – – – Negative NA – – NA
11 – + – – 1:1,600 L. bataviae – – NA
12 – + – – 1:800 L. wolffii – + L. venezuelensis
13 – + – – 1:400 L. wolffii – + L. venezuelensis
14 – + – – 1:800 L. wolffii – + L. venezuelensis
15 – – – – Negative NA – – NA
16 – + – – 1:400 L. wolffii – + L. venezuelensis

*Results for MAT serology, cultures, and PCR of the Leptospira lipL32 and rrs (16S rDNA) genes from cultured isolates. MAT, microscopic agglutination test; NA, not applicable; –, negative; +, positive. †Leptospira spp. were determined by sequencing the PCR-amplified rrs gene.

Main Article

1Current affiliation: Universidad de las Fuerzas Armadas ESPE, Santo Domingo, Ecuador.

2Current affiliation: Universidad de Buenos Aires, Buenos Aires, Argentina.

3Current affiliation: Institut Pasteur de Montevideo, Montevideo, Uruguay.

4Current affiliation: The University of North Carolina, Chapel Hill, North Carolina, USA.

Page created: May 10, 2024
Page updated: August 07, 2024
Page reviewed: August 07, 2024
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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