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Volume 30, Number 8—August 2024
Research
Scrapie Versus Chronic Wasting Disease in White-Tailed Deer
Figure 4
![Denaturation curves comparing the conformational stability of scrapie (misfolded) form of prion protein (PrPSc) in the cervical spinal cords of white-tailed deer with passage 2 WTD scrapie agent, passage 1 WTD scrapie agent, and CWD agent in study of scrapie versus CWD in white-tailed deer. The PrPSc conformational stability of like tissues did not differ significantly. CWD, chronic wasting disease; Fapp, apparent fractional change of unfolded PrPSc; GdnHCl, guanidine hydrochloride; M, molar; WTDsc-p1, passage 1 WTD scrapie; WTDsc-p2, passage 2 WTD scrapie.](/eid/images/24-0007-F4.jpg)
Figure 4. Denaturation curves comparing the conformational stability of scrapie (misfolded) form of prion protein (PrPSc) in the cervical spinal cords of white-tailed deer with passage 2 WTD scrapie agent, passage 1 WTD scrapie agent, and CWD agent in study of scrapie versus CWD in white-tailed deer. The PrPSc conformational stability of like tissues did not differ significantly. CWD, chronic wasting disease; Fapp, apparent fractional change of unfolded PrPSc; GdnHCl, guanidine hydrochloride; M, molar; WTDsc-p1, passage 1 WTD scrapie; WTDsc-p2, passage 2 WTD scrapie.
1Current affiliation: Des Moines University, Des Moines, Iowa, USA.