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Volume 22, Number 5—May 2016
Research

Plasmodium falciparum K76T pfcrt Gene Mutations and Parasite Population Structure, Haiti, 2006–2009

Macarthur Charles, Sanchita Das, Rachel Daniels, Laura Kirkman, Glavdia G. Delva, Rodney Destine, Ananias A. Escalante, Leopoldo Villegas, Noah M. Daniels, Kristi Shigyo, Sarah K. Volkman, Jean W. Pape, and Linnie M. GolightlyComments to Author 
Author affiliations: Weill Medical College of Cornell University, New York, New York, USA (M. Charles, S. Das, L. Kirkman, K. Shigyo, J.W. Pape, L.M. Golightly); The Haitian Group for the Study of Kaposi's Sarcoma and Opportunistic Infections Centers (GHESKIO); Port-au-Prince, Haiti (M. Charles, G.G. Delva, R. Destine, J.W. Pape); Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA (R. Daniels, S.K. Volkman); Broad Institute, Cambridge, Massachusetts, USA (R. Daniels, S.K. Volkman); Temple University, Department of Biology, Philadelphia, Pennsylvania, USA (A. Escalante); ICF International, Rockville, Maryland, USA (L. Villegas); Centro de Investigación de Campo Dr. Francesco Vitanza, Tumeremo, Venezuela (L. Villegas); Massachusetts Institute of Technology, Cambridge (N.M. Daniels); Simmons College, Boston (S.K. Volkman)

Main Article

Figure 1

Flowchart of blood specimen processing and analysis for study of presence of Plasmodium falciparum K76T pfcrt gene mutations, Haiti. Each sample was analyzed for the presence of pfcrt mutations associated with chloroquine drug resistance by only one method (restriction digest or sequencing) with the exception of 2 samples. pfcrt, P. falciparum chloroquine resistance transporter; CQR, chloroquine-resistant; SNP, single-nucleotide polymorphism.

Figure 1. Flowchart of blood specimen processing and analysis for study of presence of Plasmodium falciparum K76T pfcrt gene mutations, Haiti. Each sample was analyzed for the presence of pfcrt mutations associated with chloroquine drug resistance by only one method (restriction digest or sequencing) with the exception of 2 samples. pfcrt, P. falciparum chloroquine resistance transporter; CQR, chloroquine-resistant; SNP, single-nucleotide polymorphism.

Main Article

Page created: April 13, 2016
Page updated: April 13, 2016
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