Characterization of a Feline Influenza A(H7N2) Virus
, Gongxun Zhong1
, Yuwei Gao1
, Noriko Nakajima1
, Shufang Fan1
, Shiho Chiba, Kathleen M. Deering, Mutsumi Ito, Masaki Imai, Maki Kiso, Sumiho Nakatsu, Tiago J. Lopes, Andrew J. Thompson, Ryan McBride, David L. Suarez, Catherine A. Macken, Shigeo Sugita, Gabriele Neumann, Hideki Hasegawa, James C. Paulson, Kathy L. Toohey-Kurth, and Yoshihiro Kawaoka
Author affiliations: University of Wisconsin–Madison, Madison, Wisconsin, USA (M. Hatta, G. Zhong, Y. Gao, S. Fan, S. Chiba, K.M. Deering, T.J. Lopes, G. Neumann, K.L. Toohey-Kurth, Y. Kawaoka); National Institute of Infectious Diseases, Tokyo, Japan (N. Nakajima, H. Hasegawa); University of Tokyo, Tokyo (M. Ito, M. Imai, M. Kiso, S. Nakatsu, Y. Kawaoka); The Scripps Research Institute, La Jolla, California, USA (A.J. Thompson, R. McBride, J.C. Paulson); US Department of Agriculture, Athens, Georgia, USA (D.L. Suarez); The University of Auckland, Auckland, New Zealand (C. A. Macken); Japan Racing Association, Tochigi, Japan (S. Sugita)
Figure 6. Receptor-binding specificities of influenza A viruses, New York, NY, USA. A) A representative human virus, A/Kawasaki/ 173-PR8(H1N1) is shown for comparison with B) the avian influenza A(H7N2) virus A/chicken/NY/99 and C) the feline influenza A(H7N2) virus A/feline/NY/16. Receptor-binding specificities of the avian and feline viruses were compared with those of the human virus in a glycan microarray containing α2,3- and α2,6-linked sialosides. Error bars represent SDs calculated from 4 replicate spots of each glycan. RFU, relative fluorescence units. A complete list of the glycans used is shown in Technical Appendix Table 2.
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