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Volume 24, Number 1—January 2018
Research

Characterization of a Feline Influenza A(H7N2) Virus

Masato Hatta1, Gongxun Zhong1, Yuwei Gao1, Noriko Nakajima1, Shufang Fan1, Shiho Chiba, Kathleen M. Deering, Mutsumi Ito, Masaki Imai, Maki Kiso, Sumiho Nakatsu, Tiago J. Lopes, Andrew J. Thompson, Ryan McBride, David L. Suarez, Catherine A. Macken, Shigeo Sugita, Gabriele Neumann, Hideki Hasegawa, James C. Paulson, Kathy L. Toohey-Kurth, and Yoshihiro KawaokaComments to Author 
Author affiliations: University of Wisconsin–Madison, Madison, Wisconsin, USA (M. Hatta, G. Zhong, Y. Gao, S. Fan, S. Chiba, K.M. Deering, T.J. Lopes, G. Neumann, K.L. Toohey-Kurth, Y. Kawaoka); National Institute of Infectious Diseases, Tokyo, Japan (N. Nakajima, H. Hasegawa); University of Tokyo, Tokyo (M. Ito, M. Imai, M. Kiso, S. Nakatsu, Y. Kawaoka); The Scripps Research Institute, La Jolla, California, USA (A.J. Thompson, R. McBride, J.C. Paulson); US Department of Agriculture, Athens, Georgia, USA (D.L. Suarez); The University of Auckland, Auckland, New Zealand (C. A. Macken); Japan Racing Association, Tochigi, Japan (S. Sugita)

Main Article

Figure 6

Receptor-binding specificities of influenza A viruses, New York, NY, USA. A) A representative human virus, A/Kawasaki/ 173-PR8(H1N1) is shown for comparison with B) the avian influenza A(H7N2) virus A/chicken/NY/99 and C) the feline influenza A(H7N2) virus A/feline/NY/16. Receptor-binding specificities of the avian and feline viruses were compared with those of the human virus in a glycan microarray containing α2,3- and α2,6-linked sialosides. Error bars represent SDs calculated from 4 replicate

Figure 6. Receptor-binding specificities of influenza A viruses, New York, NY, USA. A) A representative human virus, A/Kawasaki/ 173-PR8(H1N1) is shown for comparison with B) the avian influenza A(H7N2) virus A/chicken/NY/99 and C) the feline influenza A(H7N2) virus A/feline/NY/16. Receptor-binding specificities of the avian and feline viruses were compared with those of the human virus in a glycan microarray containing α2,3- and α2,6-linked sialosides. Error bars represent SDs calculated from 4 replicate spots of each glycan. RFU, relative fluorescence units. A complete list of the glycans used is shown in Technical Appendix Table 2.

Main Article

1These authors contributed equally to this article.

Page created: December 19, 2017
Page updated: December 19, 2017
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