Table 3

Characterization of a Feline Influenza A(H7N2) Virus

Masato Hatta¹, Gongxun Zhong¹, Yuwei Gao¹, Noriko Nakajima¹, Shufang Fan¹, Shiho Chiba, Kathleen M. Deering, Mutsumi Ito, Masaki Imai, Maki Kiso, Sumiho Nakatsu, Tiago J. Lopes, Andrew J. Thompson, Ryan McBride, David L. Suarez, Catherine A. Macken, Shigeo Sugita, Gabriele Neumann, Hideki Hasegawa, James C. Paulson, Kathy L. Toohey-Kurth, and Yoshihiro Kawaoka

Author affiliations: University of Wisconsin–Madison, Madison, Wisconsin, USA (M. Hatta, G. Zhong, Y. Gao, S. Fan, S. Chiba, K.M. Deering, T.J. Lopes, G. Neumann, K.L. Toohey-Kurth, Y. Kawaoka); National Institute of Infectious Diseases, Tokyo, Japan (N. Nakajima, H. Hasegawa); University of Tokyo, Tokyo (M. Ito, M. Imai, M. Kiso, S. Nakatsu, Y. Kawaoka); The Scripps Research Institute, La Jolla, California, USA (A.J. Thompson, R. McBride, J.C. Paulson); US Department of Agriculture, Athens, Georgia, USA (D.L. Suarez); The University of Auckland, Auckland, New Zealand (C. A. Macken); Japan Racing Association, Tochigi, Japan (S. Sugita)

Main Article

Virus titers in nasal wash samples from ferret transmission studies*

Virus	Transmission mode	Pair	Action	Virus titers in nasal wash samples by days post-infection, exposure, or contact, log₁₀(PFU/mL)						Seroconversion (HI titer)†
Virus	Transmission mode	Pair	Action	1	3	5	7	9	11	Seroconversion (HI titer)†
A/feline/ NY/16	Respiratory droplets	1	Infection	4.2	5.6	5.0	–	–	–	320
			Exposure	–	–	–	–	–	–	<10
		2	Infection	4.6	4.3	5.4	–	–	–	320
			Exposure	–	–	–	–	–	–	<10
		3	Infection	5.3	5.0	4.8	2.8	–	–	640
			Exposure	–	–	–	–	–	–	<10
	Direct contact	1	Infection	3.6	4.1	5.0	2.0	–	–	640
			Contact	–	–	–	–	–	–	<10
		2	Infection	5.5	5.1	4.3	1.3	–	–	320
			Contact	–	–	–	–	–	–	<10
		3	Infection	5.0	5.2	5.2	2.9	–	–	640
			Contact	–	–	4.2	5.3	4.6	–	320
A/chicken/ NY/99	Respiratory droplets	1	Infection	5.8	4.0	4.3	–	–	–	160
			Exposure	–	–	–	–	–	–	<10
		2	Infection	5.6	4.2	3.5	–	–	–	160
			Exposure	–	–	–	–	–	–	<10
		3	Infection	5.1	3.7	3.5	–	–	–	320
			Exposure	–	–	–	–	–	–	<10
	Direct contact	1	Infection	4.3	4.3	3.0	–	–	–	160
			Contact	–	–	3.8	4.3	3.4	–	160
		2	Infection	4.2	3.8	3.8	–	–	–	160
			Contact	–	–	2.1	–	–	–	10
		3	Infection	4.9	3.9	4.3	–	–	–	320
			Contact	–	–	–	–	–	–	10

*–, no virus detected.
†Serum specimens were collected on day 18 after infection, exposure, or contact, and examined using an HI assay. The HI titer is the inverse of the highest dilution of serum that completely inhibited hemagglutination.

Main Article

¹These authors contributed equally to this article.

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Page updated: December 19, 2017

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