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Volume 24, Number 1—January 2018
Research

Characterization of a Feline Influenza A(H7N2) Virus

Masato Hatta1, Gongxun Zhong1, Yuwei Gao1, Noriko Nakajima1, Shufang Fan1, Shiho Chiba, Kathleen M. Deering, Mutsumi Ito, Masaki Imai, Maki Kiso, Sumiho Nakatsu, Tiago J. Lopes, Andrew J. Thompson, Ryan McBride, David L. Suarez, Catherine A. Macken, Shigeo Sugita, Gabriele Neumann, Hideki Hasegawa, James C. Paulson, Kathy L. Toohey-Kurth, and Yoshihiro KawaokaComments to Author 
Author affiliations: University of Wisconsin–Madison, Madison, Wisconsin, USA (M. Hatta, G. Zhong, Y. Gao, S. Fan, S. Chiba, K.M. Deering, T.J. Lopes, G. Neumann, K.L. Toohey-Kurth, Y. Kawaoka); National Institute of Infectious Diseases, Tokyo, Japan (N. Nakajima, H. Hasegawa); University of Tokyo, Tokyo (M. Ito, M. Imai, M. Kiso, S. Nakatsu, Y. Kawaoka); The Scripps Research Institute, La Jolla, California, USA (A.J. Thompson, R. McBride, J.C. Paulson); US Department of Agriculture, Athens, Georgia, USA (D.L. Suarez); The University of Auckland, Auckland, New Zealand (C. A. Macken); Japan Racing Association, Tochigi, Japan (S. Sugita)

Main Article

Table 4

Virus titers in nasal swab samples from cat transmission studies*

Virus
Transmission mode
Pair
Action
Virus titers in nasal swab samples by days postinfection, exposure, or contact, log10(PFU/mL) Sero-conversion
(HI titer)†
1
3
5
7
9
11
13
A/feline/NY/16 Respiratory droplets Pair 1 Infection 5.6 4.7 4.3 3.0 320

Exposure




5.2


160
Pair 2 Infection 4.5 2.7 5.0 4.6 320

Exposure





5.4

80
Pair 3 Infection 4.8 3.2 5.3 3.6 320

Exposure







<10
Direct contact Pair 1 Infection 5.9 4.6 3.4 320

Contact


2.0
5.4



320
Pair 2 Infection 6.0 5.0 4.6 640

Contact







80
Pair 3 Infection 4.9 4.9 4.4 4.2 640



Contact

5.2
5.4
5.2



160
A/chicken/NY/99 Respiratory droplets Pair 1 Infection 4.0 3.7 4.7 320

Exposure







20
Pair 2 Infection 320

Exposure







20
Pair 3 Infection 2.6 1.6 2.3 80

Exposure







160
Direct contact Pair 1 Infection 4.5 2.4 4.5 80

Contact







160
Pair 2 Infection 3.4 4.8 4.1 3.6 160

Contact







40
Pair 3 Infection 3.4 3.5 3.2 3.3 160
Contact 20

*–, no virus detected.
†Serum samples were collected on day 18 after infection, exposure, or contact, and examined by use of an HI assay. The HI titer is the inverse of the highest dilution of serum that completely inhibited hemagglutination.

Main Article

1These authors contributed equally to this article.

Page created: December 19, 2017
Page updated: December 19, 2017
Page reviewed: December 19, 2017
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