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Volume 31, Number 3—March 2025
Research

Influenza A(H5N1) Immune Response among Ferrets with Influenza A(H1N1)pdm09 Immunity

Valerie Le SageComments to Author , Bailee D. Werner, Grace A. Merrbach, Sarah E. Petnuch, Aoife K. O’Connell, Holly C. Simmons, Kevin R. McCarthy, Douglas S. Reed, Louise H. Moncla, Disha Bhavsar, Florian Krammer, Nicholas A. Crossland, Anita K. McElroy, W. Paul Duprex, and Seema S. Lakdawala
Author affiliation: Author affiliations: University of Pittsburgh, Pittsburgh, Pennsylvania, USA (V. Le Sage, B.D. Werner, G.A. Merrbach, S.E. Petnuch, H.C. Simmons, K.R. McCarthy, D.S. Reed, L.H. Moncla, A.K. McElroy, W.P. Duprex); Boston University, Boston, Massachusetts, USA (A.K. O’Connell, N.A. Crossland); Icahn School of Medicine at Mount Sinai, New York, New York, USA (D. Bhavsar, F. Krammer); Medical University of Vienna, Vienna, Austria (F. Krammer); Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA (N.A. Crossland); Emory University, Atlanta, Georgia, USA (S.S. Lakdawala)

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Figure 3

Lung infiltrates measured in a study of influenza A(H5N1) immune response among ferrets with pH1N1 immunity. We blindly scored 5 lung sections for ferrets with no prior or existing pH1N1 immunity for lung injury (A), perivascular mononuclear infiltrates (B), and BALT hyperplasia (C). Each dot represents the cumulative score of the 5 sections for each ferret. Bar values indicate means; whiskers indicate SDs. BALT, bronchus-associated lymphoid tissue; pH1N1, influenza A(H1N1)pdm09.

Figure 3. Lung infiltrates measured in a study of influenza A(H5N1) immune response among ferrets with pH1N1 immunity. We blindly scored 5 lung sections for ferrets with no prior or existing pH1N1 immunity for lung injury (A), perivascular mononuclear infiltrates (B), and BALT hyperplasia (C). Each dot represents the cumulative score of the 5 sections for each ferret. Bar values indicate means; whiskers indicate SDs. BALT, bronchus-associated lymphoid tissue; pH1N1, influenza A(H1N1)pdm09.

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Page created: January 21, 2025
Page updated: February 21, 2025
Page reviewed: February 21, 2025
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