Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link

Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released.

Volume 31, Number 3—March 2025
Research

Influenza A(H5N1) Immune Response among Ferrets with Influenza A(H1N1)pdm09 Immunity

Valerie Le SageComments to Author , Bailee D. Werner, Grace A. Merrbach, Sarah E. Petnuch, Aoife K. O’Connell, Holly C. Simmons, Kevin R. McCarthy, Douglas S. Reed, Louise H. Moncla, Disha Bhavsar, Florian Krammer, Nicholas A. Crossland, Anita K. McElroy, W. Paul Duprex, and Seema S. Lakdawala
Author affiliation: Author affiliations: University of Pittsburgh, Pittsburgh, Pennsylvania, USA (V. Le Sage, B.D. Werner, G.A. Merrbach, S.E. Petnuch, H.C. Simmons, K.R. McCarthy, D.S. Reed, L.H. Moncla, A.K. McElroy, W.P. Duprex); Boston University, Boston, Massachusetts, USA (A.K. O’Connell, N.A. Crossland); Icahn School of Medicine at Mount Sinai, New York, New York, USA (D. Bhavsar, F. Krammer); Medical University of Vienna, Vienna, Austria (F. Krammer); Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA (N.A. Crossland); Emory University, Atlanta, Georgia, USA (S.S. Lakdawala)

Main Article

Figure 7

Cumulative clinical signs scores in a study of influenza A(H5N1) immune response among ferrets with pH1N1 immunity. Ferrets with or without pH1N1 immunity were intranasally infected with H5N1 strain A/dairy cattle/Texas/24-008749-001/2024(H5N1). Clinical signs of infection were monitored each day postinfection and quantified into a cumulative signs scores based on 5 ferrets on days 1–3 and 2 ferrets on days 4­–14 postinfection or until euthanasia. pH1N1, influenza A(H1N1)pdm09.

Figure 7. Cumulative clinical signs scores in a study of influenza A(H5N1) immune response among ferrets with pH1N1 immunity. Ferrets with or without pH1N1 immunity were intranasally infected with H5N1 strain A/dairy cattle/Texas/24-008749-001/2024(H5N1). Clinical signs of infection were monitored each day postinfection and quantified into a cumulative signs scores based on 5 ferrets on days 1–3 and 2 ferrets on days 4­–14 postinfection or until euthanasia. pH1N1, influenza A(H1N1)pdm09.

Main Article

Page created: January 21, 2025
Page updated: February 21, 2025
Page reviewed: February 21, 2025
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external