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Volume 32, Number 8—August 2026

Research

Virulence of Burkholderia pseudomallei Strains from Western Hemisphere and Africa in Mice

Christopher P. Klimko, J. Matthew Meinig, Kevin D. Mlynek, Nathaniel O. Rill, Sergei S. Biryukov, Jennifer L. Dankmeyer, Annette M. Gray, Jennifer Chua, Stephanie A. Halasahoris, Michael L. Davies, Brian A. Smith, Carlos I. Rodriguez-Negron, Christopher T. Braun, Elsie E. Martinez, Jade L. Spencer, David N. Dyer, Ondraya M. Frick, Marjorie E. Torres, Mindy G. Elrod, Jay E. Gee, Christopher A. Gulvik, Zachary P. Weiner, Ju Qiu, Joel A. Bozue, David DeShazer, and Christopher K. CoteComments to Author 
Author affiliation: US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA (C.P. Klimko, J.M. Meinig, K.D. Mlynek, N.O. Rill, S.S. Biryukov, J.L. Dankmeyer, A.M. Gray, J. Chua, S.A. Halasahoris, M.L. Davies, B.A. Smith, C.I. Rodriguez-Negron, C.T. Braun, E.E. Martinez, J.L. Spencer, D.N. Dyer, O.M. Frick, M.E. Torres, J. Qiu, J.A Bozue, D. DeShazer, C.K. Cote); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M.G. Elrod, J.E. Gee, C.A. Gulvik, Z.P. Weiner)

Main Article

Figure 4

Survival rates for aerosolized challenge of Western Hemisphere and Africa Burkholderia pseudomallei strain virulence in BALB/c mouse models. We challenged BALB/c mice with 5 different doses of aerosolized B. pseudomallei isolates and observed them for 60 days (Appendix 1 Tables 1, 2). Each color represents a different dose.

Figure 4. Survival rates for aerosolized challenge of Western Hemisphere and Africa Burkholderia pseudomallei strain virulence in BALB/c mouse models. We challenged BALB/c mice with 5 different doses of aerosolized B. pseudomallei isolates and observed them for 60 days (Appendix 1 Tables 1, 2). Each color represents a different dose.

Main Article

Page created: June 09, 2026
Page updated: July 10, 2026
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