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Volume 23, Number 12—December 2017
Research

Outbreaks of Neuroinvasive Astrovirus Associated with Encephalomyelitis, Weakness, and Paralysis among Weaned Pigs, Hungary

Ákos Boros, Mihály Albert, Péter Pankovics, Hunor Bíró, Patricia A. Pesavento, Tung Gia Phan, Eric Delwart, and Gábor ReuterComments to Author 
Author affiliations: ÁNTSZ Regional Institute of State Public Health Service, Pécs, Hungary (A. Boros, P. Pankovics, G. Reuter); University of Pécs, Pécs (A. Boros, P. Pankovics, G. Reuter); Ceva Phylaxia Ltd., Budapest, Hungary (M. Albert); SHP Ltd., Kaposvár, Hungary (H. Bíró); University of California, Davis, California, USA (P.A. Pesavento); Blood Systems Research Institute, San Francisco, California, USA (T.G. Phan, E. Delwart); University of California, San Francisco (E. Delwart)

Main Article

Video

Video. Stage 1: Weaned pig with posterior weakness. In milder cases and in early stage of the disease, lesions are confined to the lumbar part of the spinal cord, resulting in posterior weakness with motor incoordination, pitching, and fibrillary muscle twitching. The consciousness is intact and the behavior and interest of this pig toward his environment is normal, just imitating the so-called rooting behavior. Stage 2: Weaned pig with serious tetraplegia. The cervical, dorsal, and lumbar parts of the spinal cord are equally affected, producing serious movement disorder of both the front and hind legs. The consciousness is intact. Stage 3: Weaned pig with end-stage encephalomyelitis. The brainstem and cerebellum are most likely affected, resulting in loss of consciousness, paresis, and serious flaccid paralysis of muscles. The animals retain their sensory functions and react to pain. (Source)

Main Article

Page created: November 16, 2017
Page updated: November 16, 2017
Page reviewed: November 16, 2017
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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