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Volume 31, Number 8—August 2025
Research
Rapid Emergence and Evolution of SARS-CoV-2 Intrahost Variants among COVID-19 Patients with Prolonged Infections, Singapore
Figure 5

Figure 5. Comparative analysis of variants among lineages and infection durations in study of rapid emergence and evolution of SARS-CoV-2 iSNVs among COVID-19 patients with prolonged infections, Singapore. A, B) Variant frequency between B.1 lineages (A) and B.6 or B.6.6 lineages (B). Red arrows indicate the appearance of intrahost D614G spike variant at nucleotide position 23403. C, D) Variant frequency between COVID-19 patients with shorter infections (<7 days) (C) and those with prolonged infections (8–40 days) (D). Colored circles represent the number of patients with co-occurring intrahost variants; circle size is proportional to patient count. iSNVs, intrahost single-nucleotide variants.