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Chapter 8 Advising Travelers with Specific Needs

Advice for Air Crews

Phyllis E. Kozarsky

OVERVIEW

As airlines expand their reach and air crews are asked to travel to more exotic destinations, these travelers need to prepare ahead of time for the exposures they may encounter. To some degree, air crews are similar to all travelers to such destinations, but the differences require some modifications of travel health guidance for several reasons:

  • Layovers are short, often 24–48 hours.
  • Travel is frequent.
  • Travel to new destinations may be on short notice.
  • Despite short travel times, air crews may be more adventuresome and thus have more risk than typical tourists.
  • Air crews may perceive themselves to be low risk because of their generally healthy status and because their in-country exposure time is short.

Given these factors, it is worth noting some guidelines for this special group. In general, air carriers traveling to destinations in the developing world try to inform their crews about health issues they may face. However, airlines do not necessarily have available on their staff occupational health or other providers who are experts in travel medicine, and may not be aware of special risks at the destinations they serve. Therefore, airlines may wish to avail themselves of professionals who are knowledgeable in the field and who can help determine recommendations for the various destinations served.

Pilots are often aware of some of the medications and classes of medications that may interfere with their flight capacity. Medications that affect the central nervous system should not be prescribed, and pilots should take a trial between trips of any new medications or those that could have side effects that may interfere with flying. Pilots and flight attendants should also be aware that certain foods and beverages contain trace amounts of products that could cause a drug screen to turn positive. If questions arise, an FAA-certified aeromedical examiner (AME) should be consulted (www.faa.gov/pilots/amelocator) who will know which medications can and cannot be taken. Sometimes medication decisions are made on a case-by-case basis. AMEs examine pilots regularly and are responsible for certifying that pilots are fit to fly.

Although any travel health provider can see and advise flight crews, it is important to ask the crew member what the airline may require, in addition to what is required or recommended to maintain the person’s health while traveling. If in doubt, the travel health provider should contact the airline medical director or occupational health department for guidance. For example, some air crews primarily fly domestic routes or routes to Western Europe or Japan, so would not fly to a region of yellow fever risk in their normal daily work. However, an airline may require that crew members without contraindications be vaccinated against yellow fever, so that the airline has flexibility to shift crews and be able to address any urgent needs.

GENERAL HEALTH MEASURES

Although pilots are required to have periodic provider visits to ensure they are fit to fly, these may not address some issues that may affect them when they travel internationally, particularly to destinations in the developing world. Flight attendants and others should also consider asking their health care providers about these recommendations:

  • Administering a periodic tuberculin skin test if traveling frequently to destinations where the prevalence of tuberculosis is much higher than in the United States, where the incidence of antimicrobial resistance is higher, or where the crew member will be in close contact with crowds (www.who.int/tb/areas-ofwork/drug-resistant-tb/en).
  • Checking at each visit to make sure that routine immunizations are up-to-date (see below).
  • Immunizing against seasonal influenza every year when the vaccine becomes available.

In addition, all medications for chronic conditions should be carried in extra quantities, as they may not be available at some locations, and even if available and less costly, may be counterfeit or of poor quality (see Chapter 2, Perspectives: Pharmaceutical Quality & Falsified Drugs). The business of manufacturing counterfeit medications in developing countries is huge and growing; it is impossible to tell from the packaging or pills if they are counterfeit. Some counterfeit drugs contain little or no active ingredient, and others contain toxic contaminants.

Vaccinations

Because of the frequency of travel to international destinations, air crews may be exposed to various diseases that are not common in the United States. For example, measles can be a life-threatening illness for adults; it is more common in most of the world, including Europe, because of lack of mandatory childhood immunization against the disease in many countries. In addition, flight crews may not have had chickenpox as children and may not have been immunized. This illness often occurs at a later age in the tropics; thus, if there is interaction with local populations in these destinations, risk for infection will be higher. International flight crews should consider a travel health visit to ensure as complete protection as possible. Some may have short notice before traveling to new destinations; thus, air crew members should be asked about this possibility during their visit, so that vaccinations for an upcoming trip—that may not be imminent—may be given, or a series may be started early. Providers should educate travelers about health risks in the various destinations; whether certain vaccinations are administered will depend on the traveler’s tolerance for risk.

All travelers should make sure they are up-todate with routine vaccinations. These vaccines include measles-mumps-rubella (MMR) vaccine, diphtheria-tetanus-pertussis vaccine, varicella (chickenpox) vaccine, polio vaccine, and the seasonal influenza vaccine (see the separate sections on these diseases in Chapter 3).

Although there are no established guidelines or recommendations for the use of travel vaccinations in pilots and other air crew members, for some it may be reasonable to offer meningococcal, Japanese encephalitis, yellow fever, and typhoid vaccines because of their frequent, short-stay, and at times unpredictable travel and destinations. Hepatitis A is advisable for all travelers and may be stressed for air crews, since limited data suggest they have low rates of protection. Hepatitis B is advisable for frequent travelers because of the unpredictability of exposure. Air crews are generally a group who travel frequently beyond work, so they should always be asked during a consultation whether they plan other travel itineraries that can be addressed at the same time.

Malaria Prophylaxis

Crew members are typically informed by their airline as to which destinations harbor malaria. Some European and Asian air carriers have longer experience flying to destinations where malaria is endemic, and these airlines have various policies with respect to its prevention. Although there may be malaria transmission in some areas of destination countries, sometimes there is none in the capitals or the larger urban areas to which the major American carriers fly (such as in China or the Philippines). This is generally not the case in sub-Saharan Africa, where there can be substantial exposure during a short 24-hour layover (although in Ethiopia, there is no malaria risk in Addis Ababa). Although there may be little risk in the hotels at the destination, risk may be increased at the international airports, during unpredictable delays in transit, and during outings on layovers. Even during short single stops (for example, in West Africa on the way to South Africa), there is some risk when the aircraft doors are open. Little published data are available on the risk of malaria for flight crews with short layovers, but some information suggests that it is less than that for tourists.

Unfortunately, experience in American and European air crews to malaria-endemic destinations has shown that air crews continue to acquire malaria, as well as develop severe and complicated disease. Some illness may result from lack of awareness of airline recommendations, failure to take precautions against mosquito bites, lack of compliance with antimalarial prophylaxis, or inaccurate information regarding toxicity of medication. Transmission can be focal and intermittent, so prophylaxis for every trip to a highly endemic region should be stressed.

Flight crew members should have easy access to educational materials and prophylaxis and, if desired, should be able to have an individual risk assessment for preventive measures. For destinations where the prevalence of malaria is high (countries in West Africa, for example), crew members should take prophylaxis for layovers. For other destinations where crews are thought to be at low risk based on local intensity of transmission, accommodations, and personal behaviors, they may be advised to use insect repellents and take other precautions to avoid mosquito bites (see Chapter 2, Protection against Mosquitoes, Ticks, & Other Arthropods) but take no prophylaxis. Flight crews should always:

  • Educate themselves as much as possible about malaria.
  • Understand the importance of personal protective measures such as repellents, and use them properly.
  • Take prophylaxis if recommended.
  • Know that if fever or chills occur after exposure, it is a medical emergency.
  • Know how they can get medical assistance at their destinations or at home in the event of symptoms or signs of malaria.

There are several options for malaria prophylaxis, depending on the destination city, although needed duration of prophylaxis and adverse effects profiles of some of the drugs make them less than desirable for air crews. Country-specific recommendations can be accessed either in this text (see Chapter 3, Yellow Fever & Malaria Information, by Country) or on the CDC Travelers’ Health website (www.cdc.gov/travel). International airlines generally prefer the combination drug atovaquone-proguanil; its adverse effect profile and its dosing make it the most suitable for air crews.

Additional information on malaria prevention may be found in Chapter 3, Malaria.

Other Vectorborne Diseases

In the last decade, several mosquitoborne viruses have emerged or reemerged, including dengue, chikungunya, and Zika (see the individual disease sections in Chapter 3). Preventing mosquito bites in tropical and subtropical destinations is critical to preventing disease. Because Zika virus infection during pregnancy can cause severe birth defects, airlines should develop flight destination policies for pilots and flight attendants who are pregnant, plan to become pregnant, or have a partner who is or may become pregnant.

Food and Water Precautions and Travelers’ Diarrhea

Pilots and air crew members should follow the same safe food and water precautions and prevention and management of travelers’ diarrhea as other travelers (see Chapter 2, Travelers’ Diarrhea). They should also be well versed in the recognition and self-treatment of moderate to severe travelers’ diarrhea to shorten the duration of illness that could affect their job performance.

Bloodborne and Sexually Transmitted Infections

Although these risks and preventions are addressed in more detail in other sections, it is worth reiterating that frequent travelers have an increased likelihood of engaging in casual and unprotected sex. It is common to think that people from all Western countries would have the same risk of HIV and other sexually transmitted infections; however, travelers have far higher rates of such infections. The risk of acquisition may be higher not only for diseases such as gonorrhea and chlamydia but also for chronic illnesses such as hepatitis B and C. Dental procedures and activities such as acupuncture, tattooing, and piercing also are ill-advised during travel to developing countries.

BIBLIOGRAPHY

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  2. Byrne N. Urban malaria risk in sub-Saharan Africa: where is the evidence? Travel Med Infect Dis. 2007 Mar;5(2):135–7.
  3. Byrne NJ, Behrens RH. Airline crews’ risk for malaria on layovers in urban sub-Saharan Africa: risk assessment and appropriate prevention policy. J Travel Med. 2004 Nov-Dec;11(6):359–63.
  4. CDC. Notes from the field: malaria imported from West Africa by flight crews—Florida and Pennsylvania, 2010. MMWR Morb Mortal Wkly Rep. 2010 Nov 5;59(43):1412.
  5. Schwartz MD, Macias-Moriarity LZ, Schelling J. Professional aircrews’ attitudes toward infectious diseases and aviation medical issues. Aviat Space Environ Med. 2012 Dec;83(12):1167–70.
  6. Selent M, de Rochars VMB, Stanek D, Bensyl D, Martin B, Cohen NJ, et al. Malaria prevention knowledge, attitudes, and practices (KAP) among international flying pilots and flight attendants of a US commercial airline. J Travel Med. 2012 Dec;19(6):366–72.
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